A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast

Bradley R. Cairns, Young Joon Kim, Michael H. Sayre, Brehon C. Laurent, Roger D. Kornberg

Research output: Contribution to journalArticle

316 Citations (Scopus)

Abstract

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.

Original languageEnglish
Pages (from-to)1950-1954
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume91
Issue number5
DOIs
Publication statusPublished - 1994 Mar 1

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Saccharomyces cerevisiae
Adenosine Triphosphatases
Yeasts
Peptides
Genes
Proteins

All Science Journal Classification (ASJC) codes

  • General

Cite this

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title = "A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast",
abstract = "A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.",
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A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast. / Cairns, Bradley R.; Kim, Young Joon; Sayre, Michael H.; Laurent, Brehon C.; Kornberg, Roger D.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 5, 01.03.1994, p. 1950-1954.

Research output: Contribution to journalArticle

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AU - Kornberg, Roger D.

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