A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast

Bradley R. Cairns, Young Joon Kim, Michael H. Sayre, Brehon C. Laurent, Roger D. Kornberg

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Abstract

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.

Original languageEnglish
Pages (from-to)1950-1954
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume91
Issue number5
DOIs
Publication statusPublished - 1994 Mar 1

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All Science Journal Classification (ASJC) codes

  • General

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