Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1) along with six flavonoids (2-7), nine phenyl glycosides (8-16) and three megastigmane glycosides (17-19) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1) was elucidated as acacetin 7-O-β-(6″-(E)-crotonylglucopyranoside). From present investigation, compound 1 and 7-19 were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family.
Bibliographical noteFunding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( NRF-2011-0025129 ) and by BrainKorea21PLUS program funded by National Research Foundation of Korea.
© 2016 Elsevier Ltd.
All Science Journal Classification (ASJC) codes
- Ecology, Evolution, Behavior and Systematics