A new flavone glycoside from the leaves of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze

Seon Ju Park; Nanyoung Kim; Guijae Yoo; Yoon Jae Kim; Taek Hwan Lee; Sun Yeou Kim; Seung Hyun Kim

doi:10.1016/j.bse.2016.05.019

A new flavone glycoside from the leaves of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze

Seon Ju Park, Nanyoung Kim, Guijae Yoo, Yoon Jae Kim, Taek Hwan Lee, Sun Yeou Kim, Seung Hyun Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1) along with six flavonoids (2-7), nine phenyl glycosides (8-16) and three megastigmane glycosides (17-19) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1) was elucidated as acacetin 7-O-β-(6″-(E)-crotonylglucopyranoside). From present investigation, compound 1 and 7-19 were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family.

Original language	English
Pages (from-to)	17-21
Number of pages	5
Journal	Biochemical Systematics and Ecology
Volume	67
DOIs	https://doi.org/10.1016/j.bse.2016.05.019
Publication status	Published - 2016 Aug 1

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( NRF-2011-0025129 ) and by BrainKorea21PLUS program funded by National Research Foundation of Korea.

All Science Journal Classification (ASJC) codes

Ecology, Evolution, Behavior and Systematics
Biochemistry

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@article{231705dc5cd94ceeaf0f2b789f076625,

title = "A new flavone glycoside from the leaves of Agastache rugosa (Fisch. & C.A.Mey.) Kuntze",

abstract = "Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1) along with six flavonoids (2-7), nine phenyl glycosides (8-16) and three megastigmane glycosides (17-19) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1) was elucidated as acacetin 7-O-β-(6″-(E)-crotonylglucopyranoside). From present investigation, compound 1 and 7-19 were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family.",

author = "Park, {Seon Ju} and Nanyoung Kim and Guijae Yoo and Kim, {Yoon Jae} and Lee, {Taek Hwan} and Kim, {Sun Yeou} and Kim, {Seung Hyun}",

note = "Funding Information: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( NRF-2011-0025129 ) and by BrainKorea21PLUS program funded by National Research Foundation of Korea. ",

year = "2016",

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doi = "10.1016/j.bse.2016.05.019",

language = "English",

volume = "67",

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AU - Park, Seon Ju

AU - Kim, Nanyoung

AU - Yoo, Guijae

AU - Kim, Yoon Jae

AU - Lee, Taek Hwan

AU - Kim, Sun Yeou

AU - Kim, Seung Hyun

N1 - Funding Information: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology ( NRF-2011-0025129 ) and by BrainKorea21PLUS program funded by National Research Foundation of Korea.

PY - 2016/8/1

Y1 - 2016/8/1

N2 - Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1) along with six flavonoids (2-7), nine phenyl glycosides (8-16) and three megastigmane glycosides (17-19) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1) was elucidated as acacetin 7-O-β-(6″-(E)-crotonylglucopyranoside). From present investigation, compound 1 and 7-19 were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family.

AB - Agastache rugosa (Fisch. & C.A.Mey.) Kuntze has been widely used as a food spice and a remedy for colds in Korea, China and Japan. In this study, one new flavone glycoside (1) along with six flavonoids (2-7), nine phenyl glycosides (8-16) and three megastigmane glycosides (17-19) were isolated from the leaves of A. rugosa. By extensive spectroscopic methods including 1D and 2D NMR, and MS data, the structure of the new compound (1) was elucidated as acacetin 7-O-β-(6″-(E)-crotonylglucopyranoside). From present investigation, compound 1 and 7-19 were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family.

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