A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate

Jong Hwa Yum, DongEun Yong, Kyungwon Lee, Hyon Suk Kim, Yunsop Chong

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a blaVIM-2 gene cassette on a class 1 integron. This finding indicates that blaVIM-2 is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.

Original languageEnglish
Pages (from-to)217-219
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume42
Issue number3
DOIs
Publication statusPublished - 2002 Apr 9

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Integrons
Serratia marcescens
Carbapenems
Serratia
Imipenem
Korea
Anti-Infective Agents
Bacillus
Genes
Urine
Infection

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

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abstract = "Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a blaVIM-2 gene cassette on a class 1 integron. This finding indicates that blaVIM-2 is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.",
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A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate. / Yum, Jong Hwa; Yong, DongEun; Lee, Kyungwon; Kim, Hyon Suk; Chong, Yunsop.

In: Diagnostic Microbiology and Infectious Disease, Vol. 42, No. 3, 09.04.2002, p. 217-219.

Research output: Contribution to journalArticle

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AU - Chong, Yunsop

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