Background and objectives: Prediction for long-term clinical outcomes in patients with non-ST elevation acute coronary syndrome is important as well as early risk stratification. The aim of this study is to develop a simple assessment tool for better early bedside risk stratification for both short- and long-term clinical outcomes. Subjects and methods: 2148 patients with non-ST-segment elevation myocardial infarction (NSTEMI) (64.9 ±12.2 years, 35.0% females) were enrolled in a nationwide prospective Korea Acute Myocardial Infarction Registry (KAMIR). A new risk score was constructed using the variables related to one year mortality: TIMI risk index (17.5-30: 1 point, > 30: 2 points), Killip class (II: 1 point, > II: 2 points) and serum creatinine (? 1.5 mg/dL: 1 point), based on the multivariate-adjusted risk relationship. The new risk score system was compared with the Global Registry of Acute Coronary Events (GRACE) and TIMI risk scores during a 12-month clinical follow-up. Results: During a one year follow-up, all causes of death occurred in 362 patients (14.3%), and 184 (8.6%) patients died in the hospital. The new risk score showed good predictive value for one year mortality. The accuracy for in-hospital and one year post-discharge mortality rates, the new risk score demonstrated significant differences in predictive accuracy when compared with TIMI and GRACE risk scores. Conclusion: A new risk score in the present study provides simplicity with accuracy simultaneously for early risk stratification, and also could be a powerful predictive tool for long-term prognosis in NSTEMI.
Bibliographical noteFunding Information:
This study was performed with the support of the Korean Circulation Society (KCS) as a memorandum of the 50th Anniversary of the KCS. The authors of this manuscript have certified that they comply with the Principles of Ethical Publishing in the International Journal of Cardiology  . Appendix A KAMIR Investigators: Myung Ho Jeong, Young Jo Kim, Chong Jin Kim, Myeong Chan Cho, Youngkeun Ahn, Jong Hyun Kim, Shung Chull Chae, Seung Ho Hur, In Whan Seong, Taek Jong Hong, Donghoon Choi, Jei Keon Chae, Jay Young Rhew, Doo Il Kim, In Ho Chae, Junghan Yoon, Bon Kwon Koo, Byung Ok Kim, Myoung Yong Lee, Kee Sik Kim, Jin Yong Hwang, Seok Kyu Oh, Nae Hee Lee, Kyoung Tae Jeong, Seung Jea Tahk, Jang Ho Bae, Seung Woon Rha, Keum Soo Park, Kyoo Rok Han, Tae Hoon Ahn, Moo Hyun Kim, Joo Young Yang, Chong Yun Rhim, Hyeon Cheol Gwon, Seong Wook Park, Young Youp Koh, Seung Jae Joo, Soo Joong Kim, Dong Kyu Jin, Jin Man Cho, Wook Sung Chung, Yang Soo Jang, Jeong Gwan Cho, Ki Bae Seung and Seung Jung Park.
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine