A novel detection for biomolecule using RF LC resonator

Young Il Kim; Yoonkwon Park; Hong Koo Baik

doi:10.1109/ICSENS.2007.4388503

A novel detection for biomolecule using RF LC resonator

Young Il Kim, Yoonkwon Park, Hong Koo Baik

Department of Materials Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

This is new approach for biomolecule detection with label free method. The designed LC resonator by the combining inductors and capacitors was fabricated by MEMS process. The measured signal difference was 1.86 dB at 2.2 GHz between the return losses of biotin and avidin. The impedances for a bare device, biotin and avidin steps were Zo*(0.803-j0.002), Zo*(0.761-j0.003) and Zo*(0.718-j0.002) according to the Smith chart, respectively. From the mentioned data, we conclude that there is no frequency shift and the return loss variation at resonance point is distinctly large. This means that the biomolecule acts as a resistance, and the decreased resistance of the resonator leads to the impedance match change.

Original language	English
Title of host publication	The 6th IEEE Conference on SENSORS, IEEE SENSORS 2007
Pages	728-731
Number of pages	4
DOIs	https://doi.org/10.1109/ICSENS.2007.4388503
Publication status	Published - 2007 Dec 1
Event	6th IEEE Conference on SENSORS, IEEE SENSORS 2007 - Atlanta, GA, United States Duration: 2007 Oct 28 → 2007 Oct 31

Other

Other	6th IEEE Conference on SENSORS, IEEE SENSORS 2007
Country	United States
City	Atlanta, GA
Period	07/10/28 → 07/10/31

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering

Access to Document

10.1109/ICSENS.2007.4388503

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Kim, Y. I., Park, Y., & Baik, H. K. (2007). A novel detection for biomolecule using RF LC resonator. In The 6th IEEE Conference on SENSORS, IEEE SENSORS 2007 (pp. 728-731). [4388503] https://doi.org/10.1109/ICSENS.2007.4388503

@inproceedings{cd309daf1b6d42b4af0953406f59add2,

title = "A novel detection for biomolecule using RF LC resonator",

abstract = "This is new approach for biomolecule detection with label free method. The designed LC resonator by the combining inductors and capacitors was fabricated by MEMS process. The measured signal difference was 1.86 dB at 2.2 GHz between the return losses of biotin and avidin. The impedances for a bare device, biotin and avidin steps were Zo*(0.803-j0.002), Zo*(0.761-j0.003) and Zo*(0.718-j0.002) according to the Smith chart, respectively. From the mentioned data, we conclude that there is no frequency shift and the return loss variation at resonance point is distinctly large. This means that the biomolecule acts as a resistance, and the decreased resistance of the resonator leads to the impedance match change.",

author = "Kim, {Young Il} and Yoonkwon Park and Baik, {Hong Koo}",

year = "2007",

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doi = "10.1109/ICSENS.2007.4388503",

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isbn = "1424412617",

pages = "728--731",

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note = "6th IEEE Conference on SENSORS, IEEE SENSORS 2007 ; Conference date: 28-10-2007 Through 31-10-2007",

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N2 - This is new approach for biomolecule detection with label free method. The designed LC resonator by the combining inductors and capacitors was fabricated by MEMS process. The measured signal difference was 1.86 dB at 2.2 GHz between the return losses of biotin and avidin. The impedances for a bare device, biotin and avidin steps were Zo*(0.803-j0.002), Zo*(0.761-j0.003) and Zo*(0.718-j0.002) according to the Smith chart, respectively. From the mentioned data, we conclude that there is no frequency shift and the return loss variation at resonance point is distinctly large. This means that the biomolecule acts as a resistance, and the decreased resistance of the resonator leads to the impedance match change.

AB - This is new approach for biomolecule detection with label free method. The designed LC resonator by the combining inductors and capacitors was fabricated by MEMS process. The measured signal difference was 1.86 dB at 2.2 GHz between the return losses of biotin and avidin. The impedances for a bare device, biotin and avidin steps were Zo*(0.803-j0.002), Zo*(0.761-j0.003) and Zo*(0.718-j0.002) according to the Smith chart, respectively. From the mentioned data, we conclude that there is no frequency shift and the return loss variation at resonance point is distinctly large. This means that the biomolecule acts as a resistance, and the decreased resistance of the resonator leads to the impedance match change.

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