A Novel Method of Steroid Delivery to Improve the Efficacy of Intralesional Injection in Keloid Treatment

Mi Yeon Cho, Ahreum Song, Kee Yang Chung, Mi Ryung Roh

Research output: Contribution to journalArticlepeer-review


BACKGROUNDKeloids are a chronic disease and cause pain, pruritus, and limitation of motion. Intralesional corticosteroid injection is the first-line treatment, but its effects can be limited, even with repeated injections.OBJECTIVETo investigate the efficacy and safety of a tunneling method of corticosteroid injection compared with conventional intralesional injection.MATERIALS AND METHODSA retrospective review was conducted of keloid patients treated with intralesional corticosteroid injection by conventional and tunneling methods.RESULTSA total of 119 cases of keloid were included in the study. Among 78 patients treated with 20 mg/mL triamcinolone, the Investigators' Global Assessment effectiveness score and Observer Scar Assessment Scale (OSAS) score were significantly higher in the tunneling group than the conventional group at 1 month. At 6 months, the tunneling group showed significantly higher effectiveness in the OSAS score than the conventional group. In the tunneling group, the interval between treatments was significantly longer than in the conventional group. The occurrence of side effects was lower in the tunneling method group than in the conventional method group.CONCLUSIONThis study reveals the benefits of the tunneling method over the conventional method for therapeutic effect and side effects in keloid treatment.

Original languageEnglish
Pages (from-to)631-635
Number of pages5
JournalDermatologic Surgery
Issue number6
Publication statusPublished - 2022 Jun 1

Bibliographical note

Funding Information:
The patients described in this manuscript have provided written informed consent for publication of their case details. This work was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korea government (MSIT) (No. 2021R1A2C1094638) and a faculty research Grant of Yonsei University College of Medicine (2019-0069).

Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Surgery
  • Dermatology


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