A one-step method for covalent bond immobilization of biomolecules on silica operated in aqueous solution

Yong Kyun Sim, Heetae Jung, Su Hyun Kim, Jung Woo Park, Woo Jin Park, Chul Ho Jun

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A simple, one-step method for covalent bond immobilization of biomolecules on silica operated in water is described. In the approach, an NHS-ester linked methallylsilane is utilized as a bifunctional linker to couple the biomolecule to the silica surface. Weak organic acid such as acetic acid activates the silica surface enough to react with bifunctional linker without destroying activity of biomolecule.

Original languageEnglish
Pages (from-to)7981-7985
Number of pages5
JournalChemical Science
Volume9
Issue number41
DOIs
Publication statusPublished - 2018

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Fingerprint Dive into the research topics of 'A one-step method for covalent bond immobilization of biomolecules on silica operated in aqueous solution'. Together they form a unique fingerprint.

  • Cite this