A personality trait contributes to the occurrence of postoperative delirium: A prospective study

Jung Eun Shin, Sunghyon Kyeong, Jong Seok Lee, Jin Young Park, Woo Suk Lee, Jae Jin Kim, Kyu Hyun Yang

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Although various physical risk factors for delirium have been identified, the effect of psychological aspects is currently unknown. This study aimed to examine psychological risk factors for postoperative delirium and to identify hidden subgroups of delirium in clinical and psychological feature space. Methods: Among 200 patients with hip fracture, 78 elderly patients were prospectively evaluated for clinical and psychological assessments before surgery. As delirium was assessed from the next day to the 7th day after surgery, postoperative delirium was found in 40 patients, but not in 38 patients. Univariate and multivariate logistic regression analyses were used to explore risk factors for postoperative delirium. Phenotypic subgroups of delirium were assessed using Topological Data Analysis, in which the significant risk factors were used for evaluating filter and distance metrics. Results: Mini-Mental State Examination, neuroticism, conscientiousness, and regional anesthesia were identified as a predictive risk factor for postoperative delirium. The filter metric showed significant negative correlations with nutrition-related factors such as total protein and albumin. When filter metric and Euclidean distances were entered, delirious patients were bifurcated as a function of personality traits and anesthesia method in the patient-patient network. Conclusions: A personality trait of neuroticism and conscientiousness may predispose elderly patients to postoperative delirium and this influence may be amplified by regional anesthesia. This study verifies the contribution of psychological risk factors to delirium and provides new insight for complex etiologies of delirium by mapping various clinical variables in the topological space.

Original languageEnglish
Article number371
JournalBMC Psychiatry
Volume16
Issue number1
DOIs
Publication statusPublished - 2016 Nov 3

Fingerprint

Delirium
Personality
Prospective Studies
Psychology
Conduction Anesthesia
Hip Fractures
Ambulatory Surgical Procedures
Albumins
Anesthesia
Logistic Models
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Cite this

Shin, Jung Eun ; Kyeong, Sunghyon ; Lee, Jong Seok ; Park, Jin Young ; Lee, Woo Suk ; Kim, Jae Jin ; Yang, Kyu Hyun. / A personality trait contributes to the occurrence of postoperative delirium : A prospective study. In: BMC Psychiatry. 2016 ; Vol. 16, No. 1.
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abstract = "Background: Although various physical risk factors for delirium have been identified, the effect of psychological aspects is currently unknown. This study aimed to examine psychological risk factors for postoperative delirium and to identify hidden subgroups of delirium in clinical and psychological feature space. Methods: Among 200 patients with hip fracture, 78 elderly patients were prospectively evaluated for clinical and psychological assessments before surgery. As delirium was assessed from the next day to the 7th day after surgery, postoperative delirium was found in 40 patients, but not in 38 patients. Univariate and multivariate logistic regression analyses were used to explore risk factors for postoperative delirium. Phenotypic subgroups of delirium were assessed using Topological Data Analysis, in which the significant risk factors were used for evaluating filter and distance metrics. Results: Mini-Mental State Examination, neuroticism, conscientiousness, and regional anesthesia were identified as a predictive risk factor for postoperative delirium. The filter metric showed significant negative correlations with nutrition-related factors such as total protein and albumin. When filter metric and Euclidean distances were entered, delirious patients were bifurcated as a function of personality traits and anesthesia method in the patient-patient network. Conclusions: A personality trait of neuroticism and conscientiousness may predispose elderly patients to postoperative delirium and this influence may be amplified by regional anesthesia. This study verifies the contribution of psychological risk factors to delirium and provides new insight for complex etiologies of delirium by mapping various clinical variables in the topological space.",
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A personality trait contributes to the occurrence of postoperative delirium : A prospective study. / Shin, Jung Eun; Kyeong, Sunghyon; Lee, Jong Seok; Park, Jin Young; Lee, Woo Suk; Kim, Jae Jin; Yang, Kyu Hyun.

In: BMC Psychiatry, Vol. 16, No. 1, 371, 03.11.2016.

Research output: Contribution to journalArticle

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AU - Shin, Jung Eun

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AU - Kim, Jae Jin

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AB - Background: Although various physical risk factors for delirium have been identified, the effect of psychological aspects is currently unknown. This study aimed to examine psychological risk factors for postoperative delirium and to identify hidden subgroups of delirium in clinical and psychological feature space. Methods: Among 200 patients with hip fracture, 78 elderly patients were prospectively evaluated for clinical and psychological assessments before surgery. As delirium was assessed from the next day to the 7th day after surgery, postoperative delirium was found in 40 patients, but not in 38 patients. Univariate and multivariate logistic regression analyses were used to explore risk factors for postoperative delirium. Phenotypic subgroups of delirium were assessed using Topological Data Analysis, in which the significant risk factors were used for evaluating filter and distance metrics. Results: Mini-Mental State Examination, neuroticism, conscientiousness, and regional anesthesia were identified as a predictive risk factor for postoperative delirium. The filter metric showed significant negative correlations with nutrition-related factors such as total protein and albumin. When filter metric and Euclidean distances were entered, delirious patients were bifurcated as a function of personality traits and anesthesia method in the patient-patient network. Conclusions: A personality trait of neuroticism and conscientiousness may predispose elderly patients to postoperative delirium and this influence may be amplified by regional anesthesia. This study verifies the contribution of psychological risk factors to delirium and provides new insight for complex etiologies of delirium by mapping various clinical variables in the topological space.

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