Achkar et al. show that a nuclear reserve pool of inactive phosphorylated HYL1, an essential cofactor for microRNA biogenesis, is resistant to dark- or shade-induced degradation. Upon light restoration, this HYL1 pool is quickly dephosphorylated to rapidly restore miRNA production and switch the developmental program to light-dependent growth.
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Developmental Biology
- Cell Biology