Abstract
In this article, we introduce a rapid and simple fabrication method to realize a 3-dimensional (3-D) microfluidic channel with a near-perfect circular cross section. This new concept of fabrication method is defined by metal wire removal process, where the metal wire such as a thin soldering wire for the 3-D circular shape is commercially available. For the microfluidic channel mold, PDMS (polydimethylsiloxane) was poured on several shapes such as 3-D circular, helix, and double helix shapes, of soldering wire and solidified. The soldering wire was then melted out by heating. With the two-step process, rapidly and simply fabricated 3-D circular microfluidic channels can be obtained. CPAE (endothelial cell line) cells were cultured inside the channel to evaluate the biocompatibility of the fabricated microfluidic channel. Our method will be very useful in making various circular shapes of 3-D microfluidic devices that need multi-depth and round corners inside the channel.
| Original language | English |
|---|---|
| Pages (from-to) | 533-540 |
| Number of pages | 8 |
| Journal | Microfluidics and Nanofluidics |
| Volume | 9 |
| Issue number | 2-3 |
| DOIs | |
| Publication status | Published - 2010 Aug 1 |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Materials Chemistry
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A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process. / Song, Suk Heung; Lee, Chang Keun; Kim, Tae Jin; Shin, In Cheol; Jun, Seong Chan; Jung, Hyo Il.
In: Microfluidics and Nanofluidics, Vol. 9, No. 2-3, 01.08.2010, p. 533-540.Research output: Contribution to journal › Article
TY - JOUR
T1 - A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process
AU - Song, Suk Heung
AU - Lee, Chang Keun
AU - Kim, Tae Jin
AU - Shin, In Cheol
AU - Jun, Seong Chan
AU - Jung, Hyo Il
PY - 2010/8/1
Y1 - 2010/8/1
N2 - In this article, we introduce a rapid and simple fabrication method to realize a 3-dimensional (3-D) microfluidic channel with a near-perfect circular cross section. This new concept of fabrication method is defined by metal wire removal process, where the metal wire such as a thin soldering wire for the 3-D circular shape is commercially available. For the microfluidic channel mold, PDMS (polydimethylsiloxane) was poured on several shapes such as 3-D circular, helix, and double helix shapes, of soldering wire and solidified. The soldering wire was then melted out by heating. With the two-step process, rapidly and simply fabricated 3-D circular microfluidic channels can be obtained. CPAE (endothelial cell line) cells were cultured inside the channel to evaluate the biocompatibility of the fabricated microfluidic channel. Our method will be very useful in making various circular shapes of 3-D microfluidic devices that need multi-depth and round corners inside the channel.
AB - In this article, we introduce a rapid and simple fabrication method to realize a 3-dimensional (3-D) microfluidic channel with a near-perfect circular cross section. This new concept of fabrication method is defined by metal wire removal process, where the metal wire such as a thin soldering wire for the 3-D circular shape is commercially available. For the microfluidic channel mold, PDMS (polydimethylsiloxane) was poured on several shapes such as 3-D circular, helix, and double helix shapes, of soldering wire and solidified. The soldering wire was then melted out by heating. With the two-step process, rapidly and simply fabricated 3-D circular microfluidic channels can be obtained. CPAE (endothelial cell line) cells were cultured inside the channel to evaluate the biocompatibility of the fabricated microfluidic channel. Our method will be very useful in making various circular shapes of 3-D microfluidic devices that need multi-depth and round corners inside the channel.
UR - http://www.scopus.com/inward/record.url?scp=77956263377&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77956263377&partnerID=8YFLogxK
U2 - 10.1007/s10404-010-0570-y
DO - 10.1007/s10404-010-0570-y
M3 - Article
AN - SCOPUS:77956263377
VL - 9
SP - 533
EP - 540
JO - Microfluidics and Nanofluidics
JF - Microfluidics and Nanofluidics
SN - 1613-4982
IS - 2-3
ER -