A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process

Suk Heung Song, Chang Keun Lee, Tae Jin Kim, In Cheol Shin, Seong Chan Jun, Hyo Il Jung

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

In this article, we introduce a rapid and simple fabrication method to realize a 3-dimensional (3-D) microfluidic channel with a near-perfect circular cross section. This new concept of fabrication method is defined by metal wire removal process, where the metal wire such as a thin soldering wire for the 3-D circular shape is commercially available. For the microfluidic channel mold, PDMS (polydimethylsiloxane) was poured on several shapes such as 3-D circular, helix, and double helix shapes, of soldering wire and solidified. The soldering wire was then melted out by heating. With the two-step process, rapidly and simply fabricated 3-D circular microfluidic channels can be obtained. CPAE (endothelial cell line) cells were cultured inside the channel to evaluate the biocompatibility of the fabricated microfluidic channel. Our method will be very useful in making various circular shapes of 3-D microfluidic devices that need multi-depth and round corners inside the channel.

Original languageEnglish
Pages (from-to)533-540
Number of pages8
JournalMicrofluidics and Nanofluidics
Volume9
Issue number2-3
DOIs
Publication statusPublished - 2010 Aug 1

Fingerprint

Microfluidics
Metals
wire
Wire
Soldering
Fabrication
fabrication
soldering
metals
cultured cells
helices
Endothelial cells
Polydimethylsiloxane
Biocompatibility
microfluidic devices
biocompatibility
Heating
heating
cross sections

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Materials Chemistry

Cite this

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abstract = "In this article, we introduce a rapid and simple fabrication method to realize a 3-dimensional (3-D) microfluidic channel with a near-perfect circular cross section. This new concept of fabrication method is defined by metal wire removal process, where the metal wire such as a thin soldering wire for the 3-D circular shape is commercially available. For the microfluidic channel mold, PDMS (polydimethylsiloxane) was poured on several shapes such as 3-D circular, helix, and double helix shapes, of soldering wire and solidified. The soldering wire was then melted out by heating. With the two-step process, rapidly and simply fabricated 3-D circular microfluidic channels can be obtained. CPAE (endothelial cell line) cells were cultured inside the channel to evaluate the biocompatibility of the fabricated microfluidic channel. Our method will be very useful in making various circular shapes of 3-D microfluidic devices that need multi-depth and round corners inside the channel.",
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A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process. / Song, Suk Heung; Lee, Chang Keun; Kim, Tae Jin; Shin, In Cheol; Jun, Seong Chan; Jung, Hyo Il.

In: Microfluidics and Nanofluidics, Vol. 9, No. 2-3, 01.08.2010, p. 533-540.

Research output: Contribution to journalArticle

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