A recent tendency of protein drug delivery system for bioefficacy improvement

Ju Young Lee, Kyung Sook Kim, Jung Hwa Lee, Sung Joo Hwang, Bong Lee, Gilson Khang, Hai Bang Lee, Moon Suk Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To date, considerable attention has been devoted to development of the protein-drug delivery system although protein-drug is limited to extensive utilizations due to the short half-life and denaturalization in physiology condition. Thus, a number of drug delivery systems are developed in order to endow stability of protein drugs and to improve their bioefficacy. In this review, we describe the recent trend of protein drug delivery such as protein drug-polymer conjugation, nano-scale carriers, hydrogels, liposome-micelles and microcapsules, important in the understanding of the basic science for protein drug delivery.

Original languageEnglish
Pages (from-to)587-593
Number of pages7
JournalTissue Engineering and Regenerative Medicine
Volume5
Issue number4-6
Publication statusPublished - 2008 Dec 1

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Biomedical Engineering

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  • Cite this

    Lee, J. Y., Kim, K. S., Lee, J. H., Hwang, S. J., Lee, B., Khang, G., Lee, H. B., & Kim, M. S. (2008). A recent tendency of protein drug delivery system for bioefficacy improvement. Tissue Engineering and Regenerative Medicine, 5(4-6), 587-593.