A Scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer

Jong Ju Jeong, Yong Sang Lee, Seung Chul Lee, Sang Wook Kang, Woong Youn Chung, Hang-Seok Chang, Won Youl Seo, Ki Jun Song, Cheong Soo Park

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Lateral neck node metastasis is an important prognostic factor in thyroid carcinoma. We developed a scoring system for use in prediction of lateral neck node metastasis from papillary thyroid cancer. In this study, 161 consecutive patients were included in the training data set. This scoring system, named the Yonsei Estimated Value (YEV) for lymph node metastasis in papillary thyroid cancer, was developed on the basis of results from multivariate logistic regression analysis of preoperative clinical and radiologic data. Sixty eight consecutive patients were included for testing of the validity of the scoring system. The equation for prediction of lateral neck node metastasis was follows: YEV (Yonsei Estimated Value) = 1/(1+X) X = Exp (5.333-[0.902 × sex]+[0.036 × age]-[1.020 × tumor size]-[0.177 × lymph node size]-[0.032 × lymph node density]) When the YEV was 0.3 or more, the probability of lateral neck node metastasis was 79.0%, with sensitivity of 76.3%, specificity of 69.8%, positive predictive value of 56.7%, and negative predictive value of 85.1% in the training set. When fine needle aspiration biopsy for suspicious lateral neck nodes is not possible, or the results are inadequate, our scoring system for prediction of lateral neck node metastasis can be helpful in optimization of the surgical extent for each patient.

Original languageEnglish
Pages (from-to)996-1000
Number of pages5
JournalJournal of Korean medical science
Volume26
Issue number8
DOIs
Publication statusPublished - 2011 Aug 1

Fingerprint

Neck
Neoplasm Metastasis
Lymph Nodes
Fine Needle Biopsy
Thyroid Neoplasms
Papillary Thyroid cancer
Logistic Models
Regression Analysis
Sensitivity and Specificity
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Jeong, Jong Ju ; Lee, Yong Sang ; Lee, Seung Chul ; Kang, Sang Wook ; Chung, Woong Youn ; Chang, Hang-Seok ; Seo, Won Youl ; Song, Ki Jun ; Park, Cheong Soo. / A Scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer. In: Journal of Korean medical science. 2011 ; Vol. 26, No. 8. pp. 996-1000.
@article{47ff79739bc14078b6772f6a6ddec514,
title = "A Scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer",
abstract = "Lateral neck node metastasis is an important prognostic factor in thyroid carcinoma. We developed a scoring system for use in prediction of lateral neck node metastasis from papillary thyroid cancer. In this study, 161 consecutive patients were included in the training data set. This scoring system, named the Yonsei Estimated Value (YEV) for lymph node metastasis in papillary thyroid cancer, was developed on the basis of results from multivariate logistic regression analysis of preoperative clinical and radiologic data. Sixty eight consecutive patients were included for testing of the validity of the scoring system. The equation for prediction of lateral neck node metastasis was follows: YEV (Yonsei Estimated Value) = 1/(1+X) X = Exp (5.333-[0.902 × sex]+[0.036 × age]-[1.020 × tumor size]-[0.177 × lymph node size]-[0.032 × lymph node density]) When the YEV was 0.3 or more, the probability of lateral neck node metastasis was 79.0{\%}, with sensitivity of 76.3{\%}, specificity of 69.8{\%}, positive predictive value of 56.7{\%}, and negative predictive value of 85.1{\%} in the training set. When fine needle aspiration biopsy for suspicious lateral neck nodes is not possible, or the results are inadequate, our scoring system for prediction of lateral neck node metastasis can be helpful in optimization of the surgical extent for each patient.",
author = "Jeong, {Jong Ju} and Lee, {Yong Sang} and Lee, {Seung Chul} and Kang, {Sang Wook} and Chung, {Woong Youn} and Hang-Seok Chang and Seo, {Won Youl} and Song, {Ki Jun} and Park, {Cheong Soo}",
year = "2011",
month = "8",
day = "1",
doi = "10.3346/jkms.2011.26.8.996",
language = "English",
volume = "26",
pages = "996--1000",
journal = "Journal of Korean Medical Science",
issn = "1011-8934",
publisher = "Korean Academy of Medical Science",
number = "8",

}

Jeong, JJ, Lee, YS, Lee, SC, Kang, SW, Chung, WY, Chang, H-S, Seo, WY, Song, KJ & Park, CS 2011, 'A Scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer', Journal of Korean medical science, vol. 26, no. 8, pp. 996-1000. https://doi.org/10.3346/jkms.2011.26.8.996

A Scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer. / Jeong, Jong Ju; Lee, Yong Sang; Lee, Seung Chul; Kang, Sang Wook; Chung, Woong Youn; Chang, Hang-Seok; Seo, Won Youl; Song, Ki Jun; Park, Cheong Soo.

In: Journal of Korean medical science, Vol. 26, No. 8, 01.08.2011, p. 996-1000.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A Scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer

AU - Jeong, Jong Ju

AU - Lee, Yong Sang

AU - Lee, Seung Chul

AU - Kang, Sang Wook

AU - Chung, Woong Youn

AU - Chang, Hang-Seok

AU - Seo, Won Youl

AU - Song, Ki Jun

AU - Park, Cheong Soo

PY - 2011/8/1

Y1 - 2011/8/1

N2 - Lateral neck node metastasis is an important prognostic factor in thyroid carcinoma. We developed a scoring system for use in prediction of lateral neck node metastasis from papillary thyroid cancer. In this study, 161 consecutive patients were included in the training data set. This scoring system, named the Yonsei Estimated Value (YEV) for lymph node metastasis in papillary thyroid cancer, was developed on the basis of results from multivariate logistic regression analysis of preoperative clinical and radiologic data. Sixty eight consecutive patients were included for testing of the validity of the scoring system. The equation for prediction of lateral neck node metastasis was follows: YEV (Yonsei Estimated Value) = 1/(1+X) X = Exp (5.333-[0.902 × sex]+[0.036 × age]-[1.020 × tumor size]-[0.177 × lymph node size]-[0.032 × lymph node density]) When the YEV was 0.3 or more, the probability of lateral neck node metastasis was 79.0%, with sensitivity of 76.3%, specificity of 69.8%, positive predictive value of 56.7%, and negative predictive value of 85.1% in the training set. When fine needle aspiration biopsy for suspicious lateral neck nodes is not possible, or the results are inadequate, our scoring system for prediction of lateral neck node metastasis can be helpful in optimization of the surgical extent for each patient.

AB - Lateral neck node metastasis is an important prognostic factor in thyroid carcinoma. We developed a scoring system for use in prediction of lateral neck node metastasis from papillary thyroid cancer. In this study, 161 consecutive patients were included in the training data set. This scoring system, named the Yonsei Estimated Value (YEV) for lymph node metastasis in papillary thyroid cancer, was developed on the basis of results from multivariate logistic regression analysis of preoperative clinical and radiologic data. Sixty eight consecutive patients were included for testing of the validity of the scoring system. The equation for prediction of lateral neck node metastasis was follows: YEV (Yonsei Estimated Value) = 1/(1+X) X = Exp (5.333-[0.902 × sex]+[0.036 × age]-[1.020 × tumor size]-[0.177 × lymph node size]-[0.032 × lymph node density]) When the YEV was 0.3 or more, the probability of lateral neck node metastasis was 79.0%, with sensitivity of 76.3%, specificity of 69.8%, positive predictive value of 56.7%, and negative predictive value of 85.1% in the training set. When fine needle aspiration biopsy for suspicious lateral neck nodes is not possible, or the results are inadequate, our scoring system for prediction of lateral neck node metastasis can be helpful in optimization of the surgical extent for each patient.

UR - http://www.scopus.com/inward/record.url?scp=80052667857&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052667857&partnerID=8YFLogxK

U2 - 10.3346/jkms.2011.26.8.996

DO - 10.3346/jkms.2011.26.8.996

M3 - Article

VL - 26

SP - 996

EP - 1000

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

SN - 1011-8934

IS - 8

ER -