A selective ATP chromogenic sensor for use in an indicator displacement assay

Narinder Singh; Doo Ok Jang

doi:10.1016/j.tetlet.2011.07.096

A selective ATP chromogenic sensor for use in an indicator displacement assay

Narinder Singh, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We synthesized a dinuclear Zn²⁺ complex that is useful as a sensor for ATP in a DMSO/H₂O (1:9, v/v) solvent system via a simple indicator displacement assay (IDA). This chromogenic sensor method can be used to analyze 0.1-2.0 μM of ATP with no interference from ADP or AMP.

Original language	English
Pages (from-to)	5094-5097
Number of pages	4
Journal	Tetrahedron Letters
Volume	52
Issue number	39
DOIs	https://doi.org/10.1016/j.tetlet.2011.07.096
Publication status	Published - 2011 Sept 28

Bibliographical note

Funding Information:
This work was supported by the Center for Bioactive Molecular Hybrids at Yonsei University and India-Korea Joint Program of Co-operation in Science &Technology, with additional support from an ISIRD grant from IIT Ropar .

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2011.07.096

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abstract = "We synthesized a dinuclear Zn2+ complex that is useful as a sensor for ATP in a DMSO/H2O (1:9, v/v) solvent system via a simple indicator displacement assay (IDA). This chromogenic sensor method can be used to analyze 0.1-2.0 μM of ATP with no interference from ADP or AMP.",

author = "Narinder Singh and Jang, {Doo Ok}",

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AU - Jang, Doo Ok

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PY - 2011/9/28

Y1 - 2011/9/28

N2 - We synthesized a dinuclear Zn2+ complex that is useful as a sensor for ATP in a DMSO/H2O (1:9, v/v) solvent system via a simple indicator displacement assay (IDA). This chromogenic sensor method can be used to analyze 0.1-2.0 μM of ATP with no interference from ADP or AMP.

AB - We synthesized a dinuclear Zn2+ complex that is useful as a sensor for ATP in a DMSO/H2O (1:9, v/v) solvent system via a simple indicator displacement assay (IDA). This chromogenic sensor method can be used to analyze 0.1-2.0 μM of ATP with no interference from ADP or AMP.

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ER -

A selective ATP chromogenic sensor for use in an indicator displacement assay

Abstract

Bibliographical note

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