A simple and direct biomolecule detection based on a microwave resonator

Yong Ho Kim, Seung Il Yoon, Sechul Park, Hyun Seok Kim, Yong Jun Kim, Hyo Il Jung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents a simple and direct biomolecule detection scheme based on a coplanar waveguide (CPW)to-slotline ring resonator whose resonant frequency is 3.4 GHz. Its sensitivity enhancing technique and characterization is also reported. When a biomolecule is attached on the resonator, it directly detects the biomolecule through its resonant frequency change without any additional transduction procedures. The microwave biosensor is composed of a substrate and a metal resonator (nickel and gold). For higher sensitivity, the structure was modified by adopting an insulation layer between a nickel and a gold layer. Two types of the microwave biosensor were characterized through biotin-streptavidin reaction. Measurement results showed that resonant frequency decreased 65 MHz and 10 MHz for the original type, and 79MHz and 18 MHz for the modified type when biotin and streptavidin is attached, respectively.

Original languageEnglish
Title of host publication2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
Pages213-216
Number of pages4
Publication statusPublished - 2006
Event2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings - Boston, MA, United States
Duration: 2006 May 72006 May 11

Publication series

Name2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
Volume2

Other

Other2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings
CountryUnited States
CityBoston, MA
Period06/5/706/5/11

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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