A Smartphone-Based Fourier Ptychographic Microscope Using the Display Screen for Illumination

Kyung Chul Lee, Kyungwon Lee, Jaewoo Jung, Se Hee Lee, Donghyun Kim, Seung Ah Lee

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


We propose a smartphone-mountable computational microscope that achieves wide-field and high-resolution imaging, based on the Fourier ptychographic (FP) microscopy technique. Our device uses the smartphone's built-in camera for microscopy imaging, the display screen for programmable illumination, and the computational power of the smartphone processors for FP image reconstruction. With a compact and lightweight optics module and a custom-built application, we can transform a regular smartphone into a high-performance microscope device with a space-bandwidth product exceeding that of regular benchtop microscopes. Our device achieves a half-pitch resolution of 870 nm over a wide field-of-view of 2.1 × 1.6 mm2 with amplitude, phase, and color imaging capabilities. We report on the design of the illumination and imaging system, our methods for fast FP reconstruction on the smartphone microscope, and the performance of the device. Using various clinical samples, we also discuss the potential of our device for clinical applications in resource-limited settings.

Original languageEnglish
Pages (from-to)1307-1315
Number of pages9
JournalACS Photonics
Issue number5
Publication statusPublished - 2021 May 19

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (No.2019R1A4A1025958) and by Veraverse Inc. The authors would like to thank Dr. Eunhyang Park for the help with the clinical Pap smear samples.

Publisher Copyright:
© 2021 American Chemical Society.

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering
  • Biotechnology


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