Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from mers in south korea

Jun Yong Choi, Jin Ok Oh, Jin Young Ahn, Heun Choi, Jung Ho Kim, Hye Seong, Su Jin Jeong, Nam Su Ku, Joon Sup Yeom, Jae Phil Choi

Research output: Contribution to journalArticle

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Abstract

We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.

Original languageEnglish
Pages (from-to)86-88
Number of pages3
JournalClinical and Experimental Vaccine Research
Volume8
Issue number1
DOIs
Publication statusPublished - 2019 Jan 1

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Republic of Korea
Coronavirus Infections
Antiviral Agents
Serum
Pneumonia
Therapeutics
Disease Outbreaks
Light

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Pharmacology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Choi, Jun Yong ; Oh, Jin Ok ; Ahn, Jin Young ; Choi, Heun ; Kim, Jung Ho ; Seong, Hye ; Jeong, Su Jin ; Ku, Nam Su ; Yeom, Joon Sup ; Choi, Jae Phil. / Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from mers in south korea. In: Clinical and Experimental Vaccine Research. 2019 ; Vol. 8, No. 1. pp. 86-88.
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Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from mers in south korea. / Choi, Jun Yong; Oh, Jin Ok; Ahn, Jin Young; Choi, Heun; Kim, Jung Ho; Seong, Hye; Jeong, Su Jin; Ku, Nam Su; Yeom, Joon Sup; Choi, Jae Phil.

In: Clinical and Experimental Vaccine Research, Vol. 8, No. 1, 01.01.2019, p. 86-88.

Research output: Contribution to journalArticle

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