We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.
Bibliographical noteFunding Information:
This work was supported by a faculty research grant of Yonsei University College of Medicine for (6-2015-0153).
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Public Health, Environmental and Occupational Health
- Infectious Diseases