Absence of residual microcalcifications in atypical ductal hyperplasia diagnosed via stereotactic vacuum-assisted breast biopsy: Is surgical excision obviated?

Inyoung Youn, minjung Kim, Hee Jung Moon, Eunkyung Kim

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Purpose: The purpose of our study was to evaluate the under­ estimation rate of atypical ductal hyperplasia (ADH) on vacuum- assisted breast biopsy (VABB), and to examine the correlation between residual microcalcifications and the underestimation rate of ADH. Methods: A retrospective study was performed on 27 women (mean age, 49.2±9.2 years) who underwent addi­ tional excision for ADH via VABB for microcalcifications ob­ served by using mammography. The mammographic findings, histopathologic diagnosis of all VABB and surgical specimens, and association of malignancy with residual microcalcifications were evaluated. The underestimation rate of ADH was also cal­ culated. Results: Of the 27 women with microcalcifications, nine were upgraded to ductal carcinoma in situ (DCIS); thus, the un­ derestimation rate was 33.3% (9/27). There was no difference in age (p=0.40) and extent of microcalcifications (p=0.10) when comparing benign and malignant cases. Six of 17 patients (35.3%) with remaining calcifications after VABB were upgraded to DCIS, and three of 10 patients (30%) with no residual calcifi­ cations after VABB were upgraded (p=1.00). Conclusion: The underestimation rate of ADH on VABB was 33.3%. Furthermore, 30% of patients with no remaining calcifications were upgraded to DCIS. Therefore, we conclude that all ADH cases diagnosed via VABB should be excised regardless of the presence of resid­ ual microcalcifications.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalJournal of Breast Cancer
Volume17
Issue number3
DOIs
Publication statusPublished - 2014 Sep 1

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Calcinosis
Carcinoma, Intraductal, Noninfiltrating
Vacuum
Breast
Biopsy
Mammography
Cations
Retrospective Studies

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

@article{f360e80efc6f4e738082dcc060ed0d8c,
title = "Absence of residual microcalcifications in atypical ductal hyperplasia diagnosed via stereotactic vacuum-assisted breast biopsy: Is surgical excision obviated?",
abstract = "Purpose: The purpose of our study was to evaluate the under­ estimation rate of atypical ductal hyperplasia (ADH) on vacuum- assisted breast biopsy (VABB), and to examine the correlation between residual microcalcifications and the underestimation rate of ADH. Methods: A retrospective study was performed on 27 women (mean age, 49.2±9.2 years) who underwent addi­ tional excision for ADH via VABB for microcalcifications ob­ served by using mammography. The mammographic findings, histopathologic diagnosis of all VABB and surgical specimens, and association of malignancy with residual microcalcifications were evaluated. The underestimation rate of ADH was also cal­ culated. Results: Of the 27 women with microcalcifications, nine were upgraded to ductal carcinoma in situ (DCIS); thus, the un­ derestimation rate was 33.3{\%} (9/27). There was no difference in age (p=0.40) and extent of microcalcifications (p=0.10) when comparing benign and malignant cases. Six of 17 patients (35.3{\%}) with remaining calcifications after VABB were upgraded to DCIS, and three of 10 patients (30{\%}) with no residual calcifi­ cations after VABB were upgraded (p=1.00). Conclusion: The underestimation rate of ADH on VABB was 33.3{\%}. Furthermore, 30{\%} of patients with no remaining calcifications were upgraded to DCIS. Therefore, we conclude that all ADH cases diagnosed via VABB should be excised regardless of the presence of resid­ ual microcalcifications.",
author = "Inyoung Youn and minjung Kim and Moon, {Hee Jung} and Eunkyung Kim",
year = "2014",
month = "9",
day = "1",
doi = "10.4048/jbc.2014.17.3.265",
language = "English",
volume = "17",
pages = "265--269",
journal = "Journal of Breast Cancer",
issn = "1738-6756",
publisher = "Korean Breast Cancer Society",
number = "3",

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TY - JOUR

T1 - Absence of residual microcalcifications in atypical ductal hyperplasia diagnosed via stereotactic vacuum-assisted breast biopsy

T2 - Is surgical excision obviated?

AU - Youn, Inyoung

AU - Kim, minjung

AU - Moon, Hee Jung

AU - Kim, Eunkyung

PY - 2014/9/1

Y1 - 2014/9/1

N2 - Purpose: The purpose of our study was to evaluate the under­ estimation rate of atypical ductal hyperplasia (ADH) on vacuum- assisted breast biopsy (VABB), and to examine the correlation between residual microcalcifications and the underestimation rate of ADH. Methods: A retrospective study was performed on 27 women (mean age, 49.2±9.2 years) who underwent addi­ tional excision for ADH via VABB for microcalcifications ob­ served by using mammography. The mammographic findings, histopathologic diagnosis of all VABB and surgical specimens, and association of malignancy with residual microcalcifications were evaluated. The underestimation rate of ADH was also cal­ culated. Results: Of the 27 women with microcalcifications, nine were upgraded to ductal carcinoma in situ (DCIS); thus, the un­ derestimation rate was 33.3% (9/27). There was no difference in age (p=0.40) and extent of microcalcifications (p=0.10) when comparing benign and malignant cases. Six of 17 patients (35.3%) with remaining calcifications after VABB were upgraded to DCIS, and three of 10 patients (30%) with no residual calcifi­ cations after VABB were upgraded (p=1.00). Conclusion: The underestimation rate of ADH on VABB was 33.3%. Furthermore, 30% of patients with no remaining calcifications were upgraded to DCIS. Therefore, we conclude that all ADH cases diagnosed via VABB should be excised regardless of the presence of resid­ ual microcalcifications.

AB - Purpose: The purpose of our study was to evaluate the under­ estimation rate of atypical ductal hyperplasia (ADH) on vacuum- assisted breast biopsy (VABB), and to examine the correlation between residual microcalcifications and the underestimation rate of ADH. Methods: A retrospective study was performed on 27 women (mean age, 49.2±9.2 years) who underwent addi­ tional excision for ADH via VABB for microcalcifications ob­ served by using mammography. The mammographic findings, histopathologic diagnosis of all VABB and surgical specimens, and association of malignancy with residual microcalcifications were evaluated. The underestimation rate of ADH was also cal­ culated. Results: Of the 27 women with microcalcifications, nine were upgraded to ductal carcinoma in situ (DCIS); thus, the un­ derestimation rate was 33.3% (9/27). There was no difference in age (p=0.40) and extent of microcalcifications (p=0.10) when comparing benign and malignant cases. Six of 17 patients (35.3%) with remaining calcifications after VABB were upgraded to DCIS, and three of 10 patients (30%) with no residual calcifi­ cations after VABB were upgraded (p=1.00). Conclusion: The underestimation rate of ADH on VABB was 33.3%. Furthermore, 30% of patients with no remaining calcifications were upgraded to DCIS. Therefore, we conclude that all ADH cases diagnosed via VABB should be excised regardless of the presence of resid­ ual microcalcifications.

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JO - Journal of Breast Cancer

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