TY - JOUR
T1 - Accessory papillary muscles and papillary muscle hypertrophy are associated with sudden cardiac arrest of unknown cause
AU - Uhm, Jae Sun
AU - Youn, Jong Chan
AU - Lee, Hye Jeong
AU - Park, Junbeom
AU - Park, Jin Kyu
AU - Shim, Chi Young
AU - Hong, Geu Ru
AU - Joung, Boyoung
AU - Pak, Hui Nam
AU - Lee, Moon Hyoung
N1 - Publisher Copyright:
© 2015 Elsevier Ireland Ltd
PY - 2015/8/5
Y1 - 2015/8/5
N2 - Background The present study was performed for elucidating the associations between the morphology of the papillary muscles (PMs) and sudden cardiac arrest (SCA). Methods We retrospectively reviewed history, laboratory data, electrocardiography, echocardiography, coronary angiography, and cardiac CT/MRI for 190 patients with SCA. The prevalence of accessory PMs and PM hypertrophy in patients with SCA of unknown cause was compared with that in patients with SCA of known causes and 98 age- and sex-matched patients without SCA. An accessory PM was defined as a PM with origins separated from the anterolateral and posteromedial PMs, or a PM that branched into two or three bellies at the base of the anterolateral or posteromedial PM. PM hypertrophy was defined as at least one of the two PMs having a diameter of ≥ 1.1 cm. Results In 49 patients (age 49.9 ± 15.9 years; 38 men) the cause of SCA was unknown, whereas 141 (age 54.2 ± 16.6 years; 121 men) had a known cause. The prevalence of accessory PMs was significantly higher in the unknown-cause group than in the known-cause group (24.5% and 7.8%, respectively; p = 0.002) or the no-SCA group (7.1%, p = 0.003). The same was true for PM hypertrophy (unknown-cause 12.2%, known-cause 2.1%, p = 0.010; no SCA group 1.0%, p = 0.006). By logistic regression, accessory PM and PM hypertrophy were independently associated with sudden cardiac arrest of unknown cause. Conclusions An accessory PM and PM hypertrophy are associated with SCA of unknown cause.
AB - Background The present study was performed for elucidating the associations between the morphology of the papillary muscles (PMs) and sudden cardiac arrest (SCA). Methods We retrospectively reviewed history, laboratory data, electrocardiography, echocardiography, coronary angiography, and cardiac CT/MRI for 190 patients with SCA. The prevalence of accessory PMs and PM hypertrophy in patients with SCA of unknown cause was compared with that in patients with SCA of known causes and 98 age- and sex-matched patients without SCA. An accessory PM was defined as a PM with origins separated from the anterolateral and posteromedial PMs, or a PM that branched into two or three bellies at the base of the anterolateral or posteromedial PM. PM hypertrophy was defined as at least one of the two PMs having a diameter of ≥ 1.1 cm. Results In 49 patients (age 49.9 ± 15.9 years; 38 men) the cause of SCA was unknown, whereas 141 (age 54.2 ± 16.6 years; 121 men) had a known cause. The prevalence of accessory PMs was significantly higher in the unknown-cause group than in the known-cause group (24.5% and 7.8%, respectively; p = 0.002) or the no-SCA group (7.1%, p = 0.003). The same was true for PM hypertrophy (unknown-cause 12.2%, known-cause 2.1%, p = 0.010; no SCA group 1.0%, p = 0.006). By logistic regression, accessory PM and PM hypertrophy were independently associated with sudden cardiac arrest of unknown cause. Conclusions An accessory PM and PM hypertrophy are associated with SCA of unknown cause.
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U2 - 10.1016/j.ijcard.2015.06.097
DO - 10.1016/j.ijcard.2015.06.097
M3 - Article
C2 - 26142977
AN - SCOPUS:84938543547
SN - 0167-5273
VL - 197
SP - 285
EP - 291
JO - International Journal of Cardiology
JF - International Journal of Cardiology
M1 - 20755
ER -