Accessory pathway-related left ventricular wall motion abnormality and the effects of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome

Jae Sun Uhm, Jong Ho Nam, Hee Tae Yu, Pil Sung Yang, Tae Hoon Kim, In Jeong Cho, ChiYoung Shim, Boyoung Joung, Geu Ru Hong, huinam pak, Moon Hyoung Lee

Research output: Contribution to journalArticle

Abstract

Introduction: The objective of the current study was to elucidate the effects of the accessory pathways (APs) on the left ventricular (LV) wall motion and radiofrequency catheter ablation (RFCA) on AP-related regional wall motion abnormality (RWMA) in patients with Wolff-Parkinson-White (WPW) syndrome. Methods and Results: We included 348 consecutive patients (age, 37.6 ± 17.3 years; men, 58.3%) with WPW syndrome who underwent RFCA for AP. We analyzed electrocardiographic data, the AP location, LV ejection fraction (LVEF), and RWMA patterns and their changes after RFCA. The locations of APs were right, septal, and left in 78, 94, and 176 patients, respectively. RWMA at the AP location (44.9%, 51.1%, and 17.6%, respectively; P < 0.001), decreased LVEF (10.3%, 6.4%, and 1.1%, respectively; P = 0.004), and dyskinesia (16.7%, 16.0%, and 1.1%, respectively; P < 0.001) were significantly more frequent in patients with a right or septal AP than in those with a left AP. In 31 of 50 patients with RWMA who underwent post-RFCA echocardiography (62.0%), RWMA was completely improved after RFCA. Right AP (odds ratio [OR], 22.084; 95% confidence interval [CI], 3.628-134.420; P = 0.001) and dyskinesia (OR, 6.275; 95% CI, 1.186-33.213; P = 0.031) were significantly associated with the absence of RWMA improvement after RFCA. Conclusions: AP-related RWMA is frequent in patients with right or septal APs. A substantial number of patients with right AP or dyskinesia may show no improvement in RWMA after RFCA.

LanguageEnglish
Pages102-108
Number of pages7
JournalJournal of Cardiovascular Electrophysiology
Volume30
Issue number1
DOIs
Publication statusPublished - 2019 Jan 1

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Wolff-Parkinson-White Syndrome
Catheter Ablation
Dyskinesias
Patient Rights
Odds Ratio
Confidence Intervals
Stroke Volume
Echocardiography

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

@article{e25eb8ed82774cdf875538a932907f7b,
title = "Accessory pathway-related left ventricular wall motion abnormality and the effects of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome",
abstract = "Introduction: The objective of the current study was to elucidate the effects of the accessory pathways (APs) on the left ventricular (LV) wall motion and radiofrequency catheter ablation (RFCA) on AP-related regional wall motion abnormality (RWMA) in patients with Wolff-Parkinson-White (WPW) syndrome. Methods and Results: We included 348 consecutive patients (age, 37.6 ± 17.3 years; men, 58.3{\%}) with WPW syndrome who underwent RFCA for AP. We analyzed electrocardiographic data, the AP location, LV ejection fraction (LVEF), and RWMA patterns and their changes after RFCA. The locations of APs were right, septal, and left in 78, 94, and 176 patients, respectively. RWMA at the AP location (44.9{\%}, 51.1{\%}, and 17.6{\%}, respectively; P < 0.001), decreased LVEF (10.3{\%}, 6.4{\%}, and 1.1{\%}, respectively; P = 0.004), and dyskinesia (16.7{\%}, 16.0{\%}, and 1.1{\%}, respectively; P < 0.001) were significantly more frequent in patients with a right or septal AP than in those with a left AP. In 31 of 50 patients with RWMA who underwent post-RFCA echocardiography (62.0{\%}), RWMA was completely improved after RFCA. Right AP (odds ratio [OR], 22.084; 95{\%} confidence interval [CI], 3.628-134.420; P = 0.001) and dyskinesia (OR, 6.275; 95{\%} CI, 1.186-33.213; P = 0.031) were significantly associated with the absence of RWMA improvement after RFCA. Conclusions: AP-related RWMA is frequent in patients with right or septal APs. A substantial number of patients with right AP or dyskinesia may show no improvement in RWMA after RFCA.",
author = "Uhm, {Jae Sun} and Nam, {Jong Ho} and Yu, {Hee Tae} and Yang, {Pil Sung} and Kim, {Tae Hoon} and Cho, {In Jeong} and ChiYoung Shim and Boyoung Joung and Hong, {Geu Ru} and huinam pak and Lee, {Moon Hyoung}",
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Accessory pathway-related left ventricular wall motion abnormality and the effects of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome. / Uhm, Jae Sun; Nam, Jong Ho; Yu, Hee Tae; Yang, Pil Sung; Kim, Tae Hoon; Cho, In Jeong; Shim, ChiYoung; Joung, Boyoung; Hong, Geu Ru; pak, huinam; Lee, Moon Hyoung.

In: Journal of Cardiovascular Electrophysiology, Vol. 30, No. 1, 01.01.2019, p. 102-108.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Accessory pathway-related left ventricular wall motion abnormality and the effects of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome

AU - Uhm, Jae Sun

AU - Nam, Jong Ho

AU - Yu, Hee Tae

AU - Yang, Pil Sung

AU - Kim, Tae Hoon

AU - Cho, In Jeong

AU - Shim, ChiYoung

AU - Joung, Boyoung

AU - Hong, Geu Ru

AU - pak, huinam

AU - Lee, Moon Hyoung

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Introduction: The objective of the current study was to elucidate the effects of the accessory pathways (APs) on the left ventricular (LV) wall motion and radiofrequency catheter ablation (RFCA) on AP-related regional wall motion abnormality (RWMA) in patients with Wolff-Parkinson-White (WPW) syndrome. Methods and Results: We included 348 consecutive patients (age, 37.6 ± 17.3 years; men, 58.3%) with WPW syndrome who underwent RFCA for AP. We analyzed electrocardiographic data, the AP location, LV ejection fraction (LVEF), and RWMA patterns and their changes after RFCA. The locations of APs were right, septal, and left in 78, 94, and 176 patients, respectively. RWMA at the AP location (44.9%, 51.1%, and 17.6%, respectively; P < 0.001), decreased LVEF (10.3%, 6.4%, and 1.1%, respectively; P = 0.004), and dyskinesia (16.7%, 16.0%, and 1.1%, respectively; P < 0.001) were significantly more frequent in patients with a right or septal AP than in those with a left AP. In 31 of 50 patients with RWMA who underwent post-RFCA echocardiography (62.0%), RWMA was completely improved after RFCA. Right AP (odds ratio [OR], 22.084; 95% confidence interval [CI], 3.628-134.420; P = 0.001) and dyskinesia (OR, 6.275; 95% CI, 1.186-33.213; P = 0.031) were significantly associated with the absence of RWMA improvement after RFCA. Conclusions: AP-related RWMA is frequent in patients with right or septal APs. A substantial number of patients with right AP or dyskinesia may show no improvement in RWMA after RFCA.

AB - Introduction: The objective of the current study was to elucidate the effects of the accessory pathways (APs) on the left ventricular (LV) wall motion and radiofrequency catheter ablation (RFCA) on AP-related regional wall motion abnormality (RWMA) in patients with Wolff-Parkinson-White (WPW) syndrome. Methods and Results: We included 348 consecutive patients (age, 37.6 ± 17.3 years; men, 58.3%) with WPW syndrome who underwent RFCA for AP. We analyzed electrocardiographic data, the AP location, LV ejection fraction (LVEF), and RWMA patterns and their changes after RFCA. The locations of APs were right, septal, and left in 78, 94, and 176 patients, respectively. RWMA at the AP location (44.9%, 51.1%, and 17.6%, respectively; P < 0.001), decreased LVEF (10.3%, 6.4%, and 1.1%, respectively; P = 0.004), and dyskinesia (16.7%, 16.0%, and 1.1%, respectively; P < 0.001) were significantly more frequent in patients with a right or septal AP than in those with a left AP. In 31 of 50 patients with RWMA who underwent post-RFCA echocardiography (62.0%), RWMA was completely improved after RFCA. Right AP (odds ratio [OR], 22.084; 95% confidence interval [CI], 3.628-134.420; P = 0.001) and dyskinesia (OR, 6.275; 95% CI, 1.186-33.213; P = 0.031) were significantly associated with the absence of RWMA improvement after RFCA. Conclusions: AP-related RWMA is frequent in patients with right or septal APs. A substantial number of patients with right AP or dyskinesia may show no improvement in RWMA after RFCA.

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U2 - 10.1111/jce.13753

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