Abstract
Drugs are well known causes of eosinophilic lung disease. In many patients, drug-induced eosinophilic lung disease presents with transient eosinophilic infiltrates that disappear after discontinuation of the drug. Some patients, however, experience a fulminant, acute eosinophilia-like disease. Recently, we experienced a case of amitriptyline-associated acute eosinophilic pneumonia with respiratory failure in a diabetic hemodialysis patient. Eight days after treatment with amitriptyline, sudden fever, chill, dry cough and dyspnea developed. Subsequently, multiple patch consolidations appeared on the chest radiographs. Bronchoalveolar lavage (BAL), established a diagnosis of acute eosinophilic pneumonia. After immediate discontinuation of amitriptyline, a rapid clinical and radiological improvement was observed. The present case indicates that the possibility of acute eosinophilic pneumonia should be fully considered in dialysis patients developing unexplained respiratory symptoms while on amitriptyline therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 357-359 |
| Number of pages | 3 |
| Journal | Yonsei medical journal |
| Volume | 42 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2001 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Acute eosinophilic pneumonia associated with amitriptyline in a hemodialysis patient. / Noh, H.; Young Kyu Lee, Kyu Lee; Shin Wook Kang, Wook Kang; Kyu Hun Choi, Hun Choi; Dae Suk Han, Suk Han; Ho Yung Lee, Yung Lee.
In: Yonsei medical journal, Vol. 42, No. 3, 01.01.2001, p. 357-359.Research output: Contribution to journal › Article
TY - JOUR
T1 - Acute eosinophilic pneumonia associated with amitriptyline in a hemodialysis patient
AU - Noh, H.
AU - Young Kyu Lee, Kyu Lee
AU - Shin Wook Kang, Wook Kang
AU - Kyu Hun Choi, Hun Choi
AU - Dae Suk Han, Suk Han
AU - Ho Yung Lee, Yung Lee
PY - 2001/1/1
Y1 - 2001/1/1
N2 - Drugs are well known causes of eosinophilic lung disease. In many patients, drug-induced eosinophilic lung disease presents with transient eosinophilic infiltrates that disappear after discontinuation of the drug. Some patients, however, experience a fulminant, acute eosinophilia-like disease. Recently, we experienced a case of amitriptyline-associated acute eosinophilic pneumonia with respiratory failure in a diabetic hemodialysis patient. Eight days after treatment with amitriptyline, sudden fever, chill, dry cough and dyspnea developed. Subsequently, multiple patch consolidations appeared on the chest radiographs. Bronchoalveolar lavage (BAL), established a diagnosis of acute eosinophilic pneumonia. After immediate discontinuation of amitriptyline, a rapid clinical and radiological improvement was observed. The present case indicates that the possibility of acute eosinophilic pneumonia should be fully considered in dialysis patients developing unexplained respiratory symptoms while on amitriptyline therapy.
AB - Drugs are well known causes of eosinophilic lung disease. In many patients, drug-induced eosinophilic lung disease presents with transient eosinophilic infiltrates that disappear after discontinuation of the drug. Some patients, however, experience a fulminant, acute eosinophilia-like disease. Recently, we experienced a case of amitriptyline-associated acute eosinophilic pneumonia with respiratory failure in a diabetic hemodialysis patient. Eight days after treatment with amitriptyline, sudden fever, chill, dry cough and dyspnea developed. Subsequently, multiple patch consolidations appeared on the chest radiographs. Bronchoalveolar lavage (BAL), established a diagnosis of acute eosinophilic pneumonia. After immediate discontinuation of amitriptyline, a rapid clinical and radiological improvement was observed. The present case indicates that the possibility of acute eosinophilic pneumonia should be fully considered in dialysis patients developing unexplained respiratory symptoms while on amitriptyline therapy.
UR - http://www.scopus.com/inward/record.url?scp=0034946437&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034946437&partnerID=8YFLogxK
U2 - 10.3349/ymj.2001.42.3.357
DO - 10.3349/ymj.2001.42.3.357
M3 - Article
C2 - 11456405
AN - SCOPUS:0034946437
VL - 42
SP - 357
EP - 359
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 3
ER -