Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis

Oidov Baatarkhuu, Hye Won Lee, Jacob George, Dashchirev Munkh-Orshikh, Baasankhuu Enkhtuvshin, Sosorbaram Ariunaa, Mohammed Eslam, Sang Hoon Ahn, Kwang Hyub Han, Do Young Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND/AIMS: Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade.

METHODS: The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken.

RESULTS: Acute hepatitis A, B and C was diagnosed in 50.9%, 26.2% and 6.0% of the cohort. Notably, 16.8% of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection.

CONCLUSIONS: Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country.

Original languageEnglish
Pages (from-to)147-153
Number of pages7
JournalClinical and Molecular Hepatology
Volume23
Issue number2
DOIs
Publication statusPublished - 2017 Jun 1

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Mongolia
Hepatitis A
Hepatitis C
Hepatitis B
Hepatitis
Hepatitis D
Hepatitis Delta Virus
Virus Diseases
Hepatitis B virus
Hepacivirus
Infection
Hepatitis A virus
Hepatitis Viruses
Superinfection
Infection Control
Liver Diseases
Age Groups
Incidence

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Molecular Biology

Cite this

Baatarkhuu, Oidov ; Lee, Hye Won ; George, Jacob ; Munkh-Orshikh, Dashchirev ; Enkhtuvshin, Baasankhuu ; Ariunaa, Sosorbaram ; Eslam, Mohammed ; Ahn, Sang Hoon ; Han, Kwang Hyub ; Kim, Do Young. / Acute hepatitis A, B and C but not D is still prevalent in Mongolia : a time trend analysis. In: Clinical and Molecular Hepatology. 2017 ; Vol. 23, No. 2. pp. 147-153.
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abstract = "BACKGROUND/AIMS: Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade.METHODS: The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken.RESULTS: Acute hepatitis A, B and C was diagnosed in 50.9{\%}, 26.2{\%} and 6.0{\%} of the cohort. Notably, 16.8{\%} of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection.CONCLUSIONS: Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country.",
author = "Oidov Baatarkhuu and Lee, {Hye Won} and Jacob George and Dashchirev Munkh-Orshikh and Baasankhuu Enkhtuvshin and Sosorbaram Ariunaa and Mohammed Eslam and Ahn, {Sang Hoon} and Han, {Kwang Hyub} and Kim, {Do Young}",
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Baatarkhuu, O, Lee, HW, George, J, Munkh-Orshikh, D, Enkhtuvshin, B, Ariunaa, S, Eslam, M, Ahn, SH, Han, KH & Kim, DY 2017, 'Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis', Clinical and Molecular Hepatology, vol. 23, no. 2, pp. 147-153. https://doi.org/10.3350/cmh.2016.0055

Acute hepatitis A, B and C but not D is still prevalent in Mongolia : a time trend analysis. / Baatarkhuu, Oidov; Lee, Hye Won; George, Jacob; Munkh-Orshikh, Dashchirev; Enkhtuvshin, Baasankhuu; Ariunaa, Sosorbaram; Eslam, Mohammed; Ahn, Sang Hoon; Han, Kwang Hyub; Kim, Do Young.

In: Clinical and Molecular Hepatology, Vol. 23, No. 2, 01.06.2017, p. 147-153.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Acute hepatitis A, B and C but not D is still prevalent in Mongolia

T2 - a time trend analysis

AU - Baatarkhuu, Oidov

AU - Lee, Hye Won

AU - George, Jacob

AU - Munkh-Orshikh, Dashchirev

AU - Enkhtuvshin, Baasankhuu

AU - Ariunaa, Sosorbaram

AU - Eslam, Mohammed

AU - Ahn, Sang Hoon

AU - Han, Kwang Hyub

AU - Kim, Do Young

PY - 2017/6/1

Y1 - 2017/6/1

N2 - BACKGROUND/AIMS: Mongolia has one of the highest hepatitis A, C, B and D infection incidences worldwide. We sought to investigate changes in the proportion of acute viral hepatitis types in Mongolia over the last decade.METHODS: The cohort comprised 546 consecutive patients clinically diagnosed with acute viral hepatitis from January 2012 to December 2014 in Ulaanbaatar Hospital, Mongolia. A time trend analysis investigating the change in proportion of acute hepatitis A virus, hepatitis C virus (HCV), hepatitis B virus (HBV) and hepatitis delta virus (HDV) infection among the cohort with respect to a previous published study was undertaken.RESULTS: Acute hepatitis A, B and C was diagnosed in 50.9%, 26.2% and 6.0% of the cohort. Notably, 16.8% of the cohort had a dual infection. The etiologies of acute viral hepatitis were varied by age groups. The most common cause of acute viral hepatitis among 2-19 year olds was hepatitis A, HBV and superinfection with HDV among 20-40 year olds, and HCV among 40-49 year olds. Patients with more than one hepatitis virus infection were significantly older, more likely to be male and had a higher prevalence of all risk factors for disease acquisition. These patients also had more severe liver disease at presentation compared to those with mono-infection.CONCLUSIONS: Acute viral hepatitis is still prevalent in Mongolia. Thus, the need for proper infection control is increasing in this country.

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Baatarkhuu O, Lee HW, George J, Munkh-Orshikh D, Enkhtuvshin B, Ariunaa S et al. Acute hepatitis A, B and C but not D is still prevalent in Mongolia: a time trend analysis. Clinical and Molecular Hepatology. 2017 Jun 1;23(2):147-153. https://doi.org/10.3350/cmh.2016.0055