Acute Monoarthritis Associated with Positively Birefringent Maltese Cross Appearing Lipid Spherules in a Hyperlipidemic Diabetic Patient

Yong Beom Park, Soo Kon Lee, Chang Ho Song, Won Ki Lee, Chan Hee Lee, Jisoo Lee

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7 Citations (Scopus)


A-63-year old man developed acute monoarthritis in the dorsum of the left foot. Polarized light microscopy of the synovial fluid from his third metatarsophalangeal joint revealed numerous positively birefringent lipid spherules with a maltese cross appearance. Positively birefringent lipid spherules can be found in association with acute, otherwise unexplained arthritis, and may induce synovial inflammation similar to that seen in other types of crystal-induced arthritis. We report a case of acute monoarthritis in which large numbers of positively birefringent lipid spherules were present in a hyperlipidemic diabetic patient.

Original languageEnglish
Pages (from-to)236-239
Number of pages4
JournalYonsei medical journal
Issue number4
Publication statusPublished - 1997 Jan 1


All Science Journal Classification (ASJC) codes

  • Medicine(all)

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