Additional targeted biopsy in clinically suspected prostate cancer: Prospective randomized comparison between contrast-enhanced ultrasound and sonoelastography guidance

Jieun Koh, Dae Chul Jung, Young Taik Oh, Moon Gyu Yoo, Songmi Noh, Kyung Hwa Han, Koon Ho Rha, Young Deuk Choi, Sung Joon Hong

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Our aim was to improve the detection of prostate cancer by evaluating whether contrast-enhanced ultrasound (CEUS) or sonoelastography (SE) is more helpful in guiding targeted biopsy (TB) performed before systematic biopsy (SB). A total of 52 patients suspected of having prostate cancer were prospectively included and randomly assigned to either the CEUS or SE group. Different, independent radiologists performed TB and twelve-core SB. Within each group, cancer detection rates based on core number were compared between SB and TB. We evaluated the effect of TB on core-based cancer detection rates between the CEUS and SE groups. Cancer detection was higher in overall TB cores 16.4% (28/171) than SB cores 11.4% (71/624) in both groups. In the SE group, TB cores revealed higher cancer detection than did SB cores from 4.49% (14/312) to 12.86% (9/70) (p = 0.01). Compared with CEUS, SE may improve detection rates when considering additional TB guidance methods.

Original languageEnglish
Pages (from-to)2836-2841
Number of pages6
JournalUltrasound in Medicine and Biology
Volume41
Issue number11
DOIs
Publication statusPublished - 2015 Nov

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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