Adjuvant effect of polyadenylic.Polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice

Sang Jin Park, Won Ho Kim, Kwang Hyub Han, Chae Yoon Chon, Ki Baik Hahm, Young Myoung Moon, Jin Kyung Kang, In Suh Park, Jung Koo Youn

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The adjuvant effect of polyadenylic.polyuridylic acid [poly(A).poly(U)] on antibody production against recombinant hepatitis B surface antigen (rHBsAg) was investigated. Immunization of adult Balb/c mice with rHBsAg plus poly(A).poly(U) elicited significantly higher antibody responses than immunization of mice immunized with rHBsAg alone. Such an adjuvant effect was evident even in mice sensitized with subimmunogenic doses of the antigen.

Original languageEnglish
Pages (from-to)513-516
Number of pages4
JournalInternational Journal of Immunopharmacology
Volume17
Issue number6
DOIs
Publication statusPublished - 1995 Jun

All Science Journal Classification (ASJC) codes

  • Immunology
  • Pharmacology

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