Adjuvant effect of polyadenylic.Polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice

Sang Jin Park, Won Ho Kim, KwangHyub Han, Chae Yoon Chon, Ki Baik Hahm, Young Myoung Moon, Jin Kyung Kang, In Suh Park, Jung Koo Youn

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The adjuvant effect of polyadenylic.polyuridylic acid [poly(A).poly(U)] on antibody production against recombinant hepatitis B surface antigen (rHBsAg) was investigated. Immunization of adult Balb/c mice with rHBsAg plus poly(A).poly(U) elicited significantly higher antibody responses than immunization of mice immunized with rHBsAg alone. Such an adjuvant effect was evident even in mice sensitized with subimmunogenic doses of the antigen.

Original languageEnglish
Pages (from-to)513-516
Number of pages4
JournalInternational Journal of Immunopharmacology
Volume17
Issue number6
DOIs
Publication statusPublished - 1995 Jan 1

Fingerprint

Poly U
Hepatitis B Surface Antigens
Antibody Formation
Immunization
Poly A-U
Poly A
Antigens

All Science Journal Classification (ASJC) codes

  • Immunology
  • Pharmacology

Cite this

Park, Sang Jin ; Kim, Won Ho ; Han, KwangHyub ; Chon, Chae Yoon ; Hahm, Ki Baik ; Moon, Young Myoung ; Kang, Jin Kyung ; Park, In Suh ; Youn, Jung Koo. / Adjuvant effect of polyadenylic.Polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice. In: International Journal of Immunopharmacology. 1995 ; Vol. 17, No. 6. pp. 513-516.
@article{138758226ce14c548a540de4c47f6424,
title = "Adjuvant effect of polyadenylic.Polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice",
abstract = "The adjuvant effect of polyadenylic.polyuridylic acid [poly(A).poly(U)] on antibody production against recombinant hepatitis B surface antigen (rHBsAg) was investigated. Immunization of adult Balb/c mice with rHBsAg plus poly(A).poly(U) elicited significantly higher antibody responses than immunization of mice immunized with rHBsAg alone. Such an adjuvant effect was evident even in mice sensitized with subimmunogenic doses of the antigen.",
author = "Park, {Sang Jin} and Kim, {Won Ho} and KwangHyub Han and Chon, {Chae Yoon} and Hahm, {Ki Baik} and Moon, {Young Myoung} and Kang, {Jin Kyung} and Park, {In Suh} and Youn, {Jung Koo}",
year = "1995",
month = "1",
day = "1",
doi = "10.1016/0192-0561(95)00031-V",
language = "English",
volume = "17",
pages = "513--516",
journal = "International Immunopharmacology",
issn = "1567-5769",
publisher = "Elsevier",
number = "6",

}

Adjuvant effect of polyadenylic.Polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice. / Park, Sang Jin; Kim, Won Ho; Han, KwangHyub; Chon, Chae Yoon; Hahm, Ki Baik; Moon, Young Myoung; Kang, Jin Kyung; Park, In Suh; Youn, Jung Koo.

In: International Journal of Immunopharmacology, Vol. 17, No. 6, 01.01.1995, p. 513-516.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Adjuvant effect of polyadenylic.Polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice

AU - Park, Sang Jin

AU - Kim, Won Ho

AU - Han, KwangHyub

AU - Chon, Chae Yoon

AU - Hahm, Ki Baik

AU - Moon, Young Myoung

AU - Kang, Jin Kyung

AU - Park, In Suh

AU - Youn, Jung Koo

PY - 1995/1/1

Y1 - 1995/1/1

N2 - The adjuvant effect of polyadenylic.polyuridylic acid [poly(A).poly(U)] on antibody production against recombinant hepatitis B surface antigen (rHBsAg) was investigated. Immunization of adult Balb/c mice with rHBsAg plus poly(A).poly(U) elicited significantly higher antibody responses than immunization of mice immunized with rHBsAg alone. Such an adjuvant effect was evident even in mice sensitized with subimmunogenic doses of the antigen.

AB - The adjuvant effect of polyadenylic.polyuridylic acid [poly(A).poly(U)] on antibody production against recombinant hepatitis B surface antigen (rHBsAg) was investigated. Immunization of adult Balb/c mice with rHBsAg plus poly(A).poly(U) elicited significantly higher antibody responses than immunization of mice immunized with rHBsAg alone. Such an adjuvant effect was evident even in mice sensitized with subimmunogenic doses of the antigen.

UR - http://www.scopus.com/inward/record.url?scp=0029100518&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029100518&partnerID=8YFLogxK

U2 - 10.1016/0192-0561(95)00031-V

DO - 10.1016/0192-0561(95)00031-V

M3 - Article

VL - 17

SP - 513

EP - 516

JO - International Immunopharmacology

JF - International Immunopharmacology

SN - 1567-5769

IS - 6

ER -