Advanced Nanomaterials for Preparedness Against (Re-)Emerging Viral Diseases

Eunjung Kim; Eun Kyung Lim; Geunseon Park; Chaewon Park; Jong Woo Lim; Hyo Lee; Woonsung Na; Minjoo Yeom; Jinyoung Kim; Daesub Song; Seungjoo Haam

doi:10.1002/adma.202005927

Advanced Nanomaterials for Preparedness Against (Re-)Emerging Viral Diseases

Eunjung Kim, Eun Kyung Lim, Geunseon Park, Chaewon Park, Jong Woo Lim, Hyo Lee, Woonsung Na, Minjoo Yeom, Jinyoung Kim, Daesub Song, Seungjoo Haam

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Review article › peer-review

14 Citations (Scopus)

Abstract

While the coronavirus disease (COVID-19) accounts for the current global pandemic, the emergence of other unknown pathogens, named “Disease X,” remains a serious concern in the future. Emerging or re-emerging pathogens continue to pose significant challenges to global public health. In response, the scientific community has been urged to create advanced platform technologies to meet the ever-increasing needs presented by these devastating diseases with pandemic potential. This review aims to bring new insights to allow for the application of advanced nanomaterials in future diagnostics, vaccines, and antiviral therapies, thereby addressing the challenges associated with the current preparedness strategies in clinical settings against viruses. The application of nanomaterials has advanced medicine and provided cutting-edge solutions for unmet needs. Herein, an overview of the currently available nanotechnologies is presented, highlighting the significant features that enable them to control infectious diseases, and identifying the challenges that remain to be addressed for the commercial production of nano-based products is presented. Finally, to conclude, the development of a nanomaterial-based system using a “One Health” approach is suggested. This strategy would require a transdisciplinary collaboration and communication between all stakeholders throughout the entire process spanning across research and development, as well as the preclinical, clinical, and manufacturing phases.

Original language	English
Article number	2005927
Journal	Advanced Materials
Volume	33
Issue number	47
DOIs	https://doi.org/10.1002/adma.202005927
Publication status	Published - 2021 Nov 25

Bibliographical note

Funding Information:
E.K., E.‐K.L., G.P., and C.P. contributed equally to this work. E.K. acknowledges support from the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2020R1F1A1066247). E.‐K.L. acknowledges support from the Basic Science Research Program of the NRF funded by MSIT (No. NRF2018R1C1B6005424), the Center for BioNano Health Guard funded by the Ministry of Science and ICT (MSIT) as a Global Frontier Project (H‐GUARD 2014M3A6B2060507), and the KRIBB Research Initiative Program. D.S. acknowledges support from the Korea Mouse Phenotyping Project (No. NRF‐2019M3A9D5A01102797) of the Ministry of Science, ICT and Future Planning through the National Research Foundation. S.H. acknowledges support from the Bio & Medical Technology Development Programs of the NRF funded by MSIT (Nos. NRF‐2018M3A9H4056340 and NRF‐2018M3A9E2022819) and the Nano Material Technology Development Program through the NRF funded by the Ministry of Education, Science and Technology (No. 2017M3A7B4041798).

Publisher Copyright:
© 2021 Wiley-VCH GmbH

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

@article{c10515d03bff4ebf8f83bcbcfe7f24c7,

title = "Advanced Nanomaterials for Preparedness Against (Re-)Emerging Viral Diseases",

abstract = "While the coronavirus disease (COVID-19) accounts for the current global pandemic, the emergence of other unknown pathogens, named “Disease X,” remains a serious concern in the future. Emerging or re-emerging pathogens continue to pose significant challenges to global public health. In response, the scientific community has been urged to create advanced platform technologies to meet the ever-increasing needs presented by these devastating diseases with pandemic potential. This review aims to bring new insights to allow for the application of advanced nanomaterials in future diagnostics, vaccines, and antiviral therapies, thereby addressing the challenges associated with the current preparedness strategies in clinical settings against viruses. The application of nanomaterials has advanced medicine and provided cutting-edge solutions for unmet needs. Herein, an overview of the currently available nanotechnologies is presented, highlighting the significant features that enable them to control infectious diseases, and identifying the challenges that remain to be addressed for the commercial production of nano-based products is presented. Finally, to conclude, the development of a nanomaterial-based system using a “One Health” approach is suggested. This strategy would require a transdisciplinary collaboration and communication between all stakeholders throughout the entire process spanning across research and development, as well as the preclinical, clinical, and manufacturing phases.",

author = "Eunjung Kim and Lim, {Eun Kyung} and Geunseon Park and Chaewon Park and Lim, {Jong Woo} and Hyo Lee and Woonsung Na and Minjoo Yeom and Jinyoung Kim and Daesub Song and Seungjoo Haam",

note = "Funding Information: E.K., E.‐K.L., G.P., and C.P. contributed equally to this work. E.K. acknowledges support from the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2020R1F1A1066247). E.‐K.L. acknowledges support from the Basic Science Research Program of the NRF funded by MSIT (No. NRF2018R1C1B6005424), the Center for BioNano Health Guard funded by the Ministry of Science and ICT (MSIT) as a Global Frontier Project (H‐GUARD 2014M3A6B2060507), and the KRIBB Research Initiative Program. D.S. acknowledges support from the Korea Mouse Phenotyping Project (No. NRF‐2019M3A9D5A01102797) of the Ministry of Science, ICT and Future Planning through the National Research Foundation. S.H. acknowledges support from the Bio & Medical Technology Development Programs of the NRF funded by MSIT (Nos. NRF‐2018M3A9H4056340 and NRF‐2018M3A9E2022819) and the Nano Material Technology Development Program through the NRF funded by the Ministry of Education, Science and Technology (No. 2017M3A7B4041798). Publisher Copyright: {\textcopyright} 2021 Wiley-VCH GmbH",

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AU - Kim, Eunjung

AU - Lim, Eun Kyung

AU - Park, Geunseon

AU - Park, Chaewon

AU - Lim, Jong Woo

AU - Lee, Hyo

AU - Na, Woonsung

AU - Yeom, Minjoo

AU - Kim, Jinyoung

AU - Song, Daesub

AU - Haam, Seungjoo

N1 - Funding Information: E.K., E.‐K.L., G.P., and C.P. contributed equally to this work. E.K. acknowledges support from the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2020R1F1A1066247). E.‐K.L. acknowledges support from the Basic Science Research Program of the NRF funded by MSIT (No. NRF2018R1C1B6005424), the Center for BioNano Health Guard funded by the Ministry of Science and ICT (MSIT) as a Global Frontier Project (H‐GUARD 2014M3A6B2060507), and the KRIBB Research Initiative Program. D.S. acknowledges support from the Korea Mouse Phenotyping Project (No. NRF‐2019M3A9D5A01102797) of the Ministry of Science, ICT and Future Planning through the National Research Foundation. S.H. acknowledges support from the Bio & Medical Technology Development Programs of the NRF funded by MSIT (Nos. NRF‐2018M3A9H4056340 and NRF‐2018M3A9E2022819) and the Nano Material Technology Development Program through the NRF funded by the Ministry of Education, Science and Technology (No. 2017M3A7B4041798). Publisher Copyright: © 2021 Wiley-VCH GmbH

PY - 2021/11/25

Y1 - 2021/11/25

N2 - While the coronavirus disease (COVID-19) accounts for the current global pandemic, the emergence of other unknown pathogens, named “Disease X,” remains a serious concern in the future. Emerging or re-emerging pathogens continue to pose significant challenges to global public health. In response, the scientific community has been urged to create advanced platform technologies to meet the ever-increasing needs presented by these devastating diseases with pandemic potential. This review aims to bring new insights to allow for the application of advanced nanomaterials in future diagnostics, vaccines, and antiviral therapies, thereby addressing the challenges associated with the current preparedness strategies in clinical settings against viruses. The application of nanomaterials has advanced medicine and provided cutting-edge solutions for unmet needs. Herein, an overview of the currently available nanotechnologies is presented, highlighting the significant features that enable them to control infectious diseases, and identifying the challenges that remain to be addressed for the commercial production of nano-based products is presented. Finally, to conclude, the development of a nanomaterial-based system using a “One Health” approach is suggested. This strategy would require a transdisciplinary collaboration and communication between all stakeholders throughout the entire process spanning across research and development, as well as the preclinical, clinical, and manufacturing phases.

AB - While the coronavirus disease (COVID-19) accounts for the current global pandemic, the emergence of other unknown pathogens, named “Disease X,” remains a serious concern in the future. Emerging or re-emerging pathogens continue to pose significant challenges to global public health. In response, the scientific community has been urged to create advanced platform technologies to meet the ever-increasing needs presented by these devastating diseases with pandemic potential. This review aims to bring new insights to allow for the application of advanced nanomaterials in future diagnostics, vaccines, and antiviral therapies, thereby addressing the challenges associated with the current preparedness strategies in clinical settings against viruses. The application of nanomaterials has advanced medicine and provided cutting-edge solutions for unmet needs. Herein, an overview of the currently available nanotechnologies is presented, highlighting the significant features that enable them to control infectious diseases, and identifying the challenges that remain to be addressed for the commercial production of nano-based products is presented. Finally, to conclude, the development of a nanomaterial-based system using a “One Health” approach is suggested. This strategy would require a transdisciplinary collaboration and communication between all stakeholders throughout the entire process spanning across research and development, as well as the preclinical, clinical, and manufacturing phases.

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Advanced Nanomaterials for Preparedness Against (Re-)Emerging Viral Diseases

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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