Advanced packaging for distribution and storage of COVID-19 vaccines: a review

Dakuri Ramakanth, Suman Singh, Pradip K. Maji, Youn Suk Lee, Kirtiraj K. Gaikwad

Research output: Contribution to journalReview articlepeer-review

16 Citations (Scopus)


The outbreak of the coronavirus disease 2019 global pandemic (COVID-19) has affected billions of lives, posing critical challenges to the healthcare system, vaccine manufacturers, packaging scientists, and daily public activity. Biotechnological advances have allowed to create rapidly vaccines, yet the success of an efficient immunization mainly depends on the safe and timely delivery of vaccines. In particular, packaging plays a crucial role in protecting, preserving, transporting, and distributing vaccines. Here, we review advanced packaging for distribution and storage of COVID-19 vaccines, with focus on innovative hybrid packaging materials, cyclic olefin polymers with nanolayer glass, and vials for vaccines. We present vaccine packaging, auto-disable syringes, stoppers, and closures. We discuss the chronology of the packaging system, and the labeling of the vaccine packages, with emphasis on bar codes, quick response codes, vaccine vial monitors, anti-counterfeiting and traceability measures.

Original languageEnglish
Pages (from-to)3597-3608
Number of pages12
JournalEnvironmental Chemistry Letters
Issue number5
Publication statusPublished - 2021 Oct

Bibliographical note

Funding Information:
Author Dakuri Ramakanth would like to thank the Ministry of Human Resources and Development (MHRD), Government of India, for providing financial support to carry out this research work.

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG.

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry


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