Abstract
Methods Nine thousand three hundred fifty-four Chinese children, ages 5-17 years old, from 24 elementary schools and 24 middle schools in the Seven Northeastern Cities during 2012-2013 were evaluated. The weight, height, and BP were measured. Four-year average concentrations of particles with an aerodynamic diameter of ≤10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), ozone (O3), and carbon monoxide (CO) were calculated from monitoring stations. Two-level regression analysis was used to examine the effects, controlling for covariates.
Results The results showed that associations existed between hypertension and pollutants. The odds ratios for hypertension ranged from 1.12 per 46.3 μg/m3 increase for O2 (95% confidence interval [CI], 1.10-1.13) to 1.68 per 30.6 μg/m3 increase for PM10 (95% CI, 1.53-1.86). The increases in mean diastolic BP ranged from 0.58 mm Hg per 46.3 μg/m3 increase for O2 (95% CI, 0.52-0.63 mm Hg) to 2.89 mm Hg per 563.4 μg/m3 increase for CO (95% CI: 2.53-3.24 mm Hg). The increase in systolic BP ranged from 0.50 mm Hg per 46.3 μg/m3 increase for O2 (95% CI: 0.43-0.57 mm Hg) to 2.10 mm Hg per 30.6 μg/m3 increase for PM10 (95% CI, 1.73-2.47 mm Hg). Compared with children who had been breastfed, non-breastfed children exhibited consistently stronger effects. Conclusion Study findings indicate that high levels of PM10, SO2, NO2, O3, and CO are associated with increased arterial BP and hypertension among the children. Breastfeeding may reduce the risk.
Background Little is known about the association between air pollution and hypertension among children, and no studies report whether breastfeeding modifies this association in children.
| Original language | English |
|---|---|
| Pages (from-to) | 956-961 |
| Number of pages | 6 |
| Journal | International Journal of Cardiology |
| Volume | 176 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2014 Oct 20 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine
Cite this
}
Air pollution associated hypertension and increased blood pressure may be reduced by breastfeeding in Chinese children : The Seven Northeastern Cities Chinese Children's Study. / Dong, Guang Hui; Qian, Zhengmin; Trevathan, Edwin; Zeng, Xiao Wen; Vaughn, Michael George; Wang, Jing; Zhao, Yang; Liu, Yu Qin; Ren, Wan Hui; Qin, Xiao Di.
In: International Journal of Cardiology, Vol. 176, No. 3, 20.10.2014, p. 956-961.Research output: Contribution to journal › Article
TY - JOUR
T1 - Air pollution associated hypertension and increased blood pressure may be reduced by breastfeeding in Chinese children
T2 - The Seven Northeastern Cities Chinese Children's Study
AU - Dong, Guang Hui
AU - Qian, Zhengmin
AU - Trevathan, Edwin
AU - Zeng, Xiao Wen
AU - Vaughn, Michael George
AU - Wang, Jing
AU - Zhao, Yang
AU - Liu, Yu Qin
AU - Ren, Wan Hui
AU - Qin, Xiao Di
PY - 2014/10/20
Y1 - 2014/10/20
N2 - Methods Nine thousand three hundred fifty-four Chinese children, ages 5-17 years old, from 24 elementary schools and 24 middle schools in the Seven Northeastern Cities during 2012-2013 were evaluated. The weight, height, and BP were measured. Four-year average concentrations of particles with an aerodynamic diameter of ≤10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), ozone (O3), and carbon monoxide (CO) were calculated from monitoring stations. Two-level regression analysis was used to examine the effects, controlling for covariates.Results The results showed that associations existed between hypertension and pollutants. The odds ratios for hypertension ranged from 1.12 per 46.3 μg/m3 increase for O2 (95% confidence interval [CI], 1.10-1.13) to 1.68 per 30.6 μg/m3 increase for PM10 (95% CI, 1.53-1.86). The increases in mean diastolic BP ranged from 0.58 mm Hg per 46.3 μg/m3 increase for O2 (95% CI, 0.52-0.63 mm Hg) to 2.89 mm Hg per 563.4 μg/m3 increase for CO (95% CI: 2.53-3.24 mm Hg). The increase in systolic BP ranged from 0.50 mm Hg per 46.3 μg/m3 increase for O2 (95% CI: 0.43-0.57 mm Hg) to 2.10 mm Hg per 30.6 μg/m3 increase for PM10 (95% CI, 1.73-2.47 mm Hg). Compared with children who had been breastfed, non-breastfed children exhibited consistently stronger effects. Conclusion Study findings indicate that high levels of PM10, SO2, NO2, O3, and CO are associated with increased arterial BP and hypertension among the children. Breastfeeding may reduce the risk.Background Little is known about the association between air pollution and hypertension among children, and no studies report whether breastfeeding modifies this association in children.
AB - Methods Nine thousand three hundred fifty-four Chinese children, ages 5-17 years old, from 24 elementary schools and 24 middle schools in the Seven Northeastern Cities during 2012-2013 were evaluated. The weight, height, and BP were measured. Four-year average concentrations of particles with an aerodynamic diameter of ≤10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxides (NO2), ozone (O3), and carbon monoxide (CO) were calculated from monitoring stations. Two-level regression analysis was used to examine the effects, controlling for covariates.Results The results showed that associations existed between hypertension and pollutants. The odds ratios for hypertension ranged from 1.12 per 46.3 μg/m3 increase for O2 (95% confidence interval [CI], 1.10-1.13) to 1.68 per 30.6 μg/m3 increase for PM10 (95% CI, 1.53-1.86). The increases in mean diastolic BP ranged from 0.58 mm Hg per 46.3 μg/m3 increase for O2 (95% CI, 0.52-0.63 mm Hg) to 2.89 mm Hg per 563.4 μg/m3 increase for CO (95% CI: 2.53-3.24 mm Hg). The increase in systolic BP ranged from 0.50 mm Hg per 46.3 μg/m3 increase for O2 (95% CI: 0.43-0.57 mm Hg) to 2.10 mm Hg per 30.6 μg/m3 increase for PM10 (95% CI, 1.73-2.47 mm Hg). Compared with children who had been breastfed, non-breastfed children exhibited consistently stronger effects. Conclusion Study findings indicate that high levels of PM10, SO2, NO2, O3, and CO are associated with increased arterial BP and hypertension among the children. Breastfeeding may reduce the risk.Background Little is known about the association between air pollution and hypertension among children, and no studies report whether breastfeeding modifies this association in children.
UR - http://www.scopus.com/inward/record.url?scp=84908176180&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908176180&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2014.08.099
DO - 10.1016/j.ijcard.2014.08.099
M3 - Article
C2 - 25186732
AN - SCOPUS:84908176180
VL - 176
SP - 956
EP - 961
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
IS - 3
ER -