Alcoholic liver disease: Treatment

Research output: Contribution to journalReview article

29 Citations (Scopus)

Abstract

The excess consumption of alcohol is associated with alcoholic liver diseases (ALD). ALD is a major healthcare problem, personal and social burden, and significant reason for economic loss worldwide. The ALD spectrum includes alcoholic fatty liver, alcoholic hepatitis, cirrhosis, and the development of hepatocellular carcinoma. The diagnosis of ALD is based on a combination of clinical features, including a history of significant alcohol intake, evidence of liver disease, and laboratory findings. Abstinence is the most important treatment for ALD and the treatment plan varies according to the stage of the disease. Various treatments including abstinence, nutritional therapy, pharmacological therapy, psychotherapy, and surgery are currently available. For severe alcoholic hepatitis, corticosteroid or pentoxifylline are recommended based on the guidelines. In addition, new therapeutic targets are being under investigation.

Original languageEnglish
Pages (from-to)12934-12944
Number of pages11
JournalWorld Journal of Gastroenterology
Volume20
Issue number36
DOIs
Publication statusPublished - 2014 Sep 28

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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