An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67

Hee Jae Shin, M. A.Mojid Mondol, Tae Kyung Yu, Hyi Seung Lee, Yeon Ju Lee, Hye Jin Jung, Jong Hyeon Kim, Ho Jeong Kwon

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14 Citations (Scopus)

Abstract

Cyclo-(l-Pro-l-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively.

Original languageEnglish
Pages (from-to)194-197
Number of pages4
JournalPhytochemistry Letters
Volume3
Issue number4
DOIs
Publication statusPublished - 2010 Dec 17

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Agronomy and Crop Science
  • Plant Science

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    Shin, H. J., Mondol, M. A. M., Yu, T. K., Lee, H. S., Lee, Y. J., Jung, H. J., Kim, J. H., & Kwon, H. J. (2010). An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67. Phytochemistry Letters, 3(4), 194-197. https://doi.org/10.1016/j.phytol.2010.07.005