An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67

Hee Jae Shin, M. A.Mojid Mondol, Tae Kyung Yu, Hyi Seung Lee, Yeon Ju Lee, Hye Jin Jung, Jong Hyeon Kim, Ho Jeong Kwon

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Cyclo-(l-Pro-l-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively.

Original languageEnglish
Pages (from-to)194-197
Number of pages4
JournalPhytochemistry Letters
Volume3
Issue number4
DOIs
Publication statusPublished - 2010 Dec 17

Fingerprint

Nocardiopsis
Chromatographic analysis
Stereochemistry
Angiogenesis Inhibitors
Actinobacteria
Endothelial cells
Human Umbilical Vein Endothelial Cells
stereochemistry
angiogenesis
Fermentation
Chromatography
data analysis
chromatography
fermentation
methodology
human umbilical vein endothelial cells

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry
  • Agronomy and Crop Science
  • Plant Science

Cite this

Shin, Hee Jae ; Mondol, M. A.Mojid ; Yu, Tae Kyung ; Lee, Hyi Seung ; Lee, Yeon Ju ; Jung, Hye Jin ; Kim, Jong Hyeon ; Kwon, Ho Jeong. / An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67. In: Phytochemistry Letters. 2010 ; Vol. 3, No. 4. pp. 194-197.
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An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67. / Shin, Hee Jae; Mondol, M. A.Mojid; Yu, Tae Kyung; Lee, Hyi Seung; Lee, Yeon Ju; Jung, Hye Jin; Kim, Jong Hyeon; Kwon, Ho Jeong.

In: Phytochemistry Letters, Vol. 3, No. 4, 17.12.2010, p. 194-197.

Research output: Contribution to journalArticle

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AU - Lee, Hyi Seung

AU - Lee, Yeon Ju

AU - Jung, Hye Jin

AU - Kim, Jong Hyeon

AU - Kwon, Ho Jeong

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