An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA

Myungjin Han, Go Eun Ha, Eunji Cheong, Gunhee Han, Youngcheol Chae

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A compact area/power efficient electrode-matched neural-spike detector (NSD) is proposed to provide an implantable multi-electrode array (MEA). A correlation scheme with only the input sampling capacitors makes an area reduction, and the recording of neural-spike events enables a power reduction, showing 0.0044 mm 2 and 0.55 μW. Together with proposed NSD, an implantable 256-channel MEA is fabricated. The electrical measurement results show that the NSD achieves an input-referred noise of 10.1 μV rms with 1 kHz to 10 kHz bandwidth, providing NEF/PEF/AEF of 1.71/5.28/0.0044, respectively, and CMRR of 67.5 dB. It shows ×7.5/×1.6 area/power improvements, compared to previous state-of-the-art NSDs. The fabricated implantable MEA is demonstrated by cell-cultured and brain-sliced experiments.

Original languageEnglish
Title of host publication2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1-4
Number of pages4
ISBN (Electronic)9781509058037
DOIs
Publication statusPublished - 2018 Mar 23
Event2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Torino, Italy
Duration: 2017 Oct 192017 Oct 21

Publication series

Name2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings
Volume2018-January

Other

Other2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017
CountryItaly
CityTorino
Period17/10/1917/10/21

Fingerprint

spikes
Detectors
Electrodes
electrodes
detectors
cultured cells
electrical measurement
brain
Brain
capacitors
Capacitors
recording
sampling
Sampling
bandwidth
Bandwidth
Experiments

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Instrumentation

Cite this

Han, M., Ha, G. E., Cheong, E., Han, G., & Chae, Y. (2018). An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA. In 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings (pp. 1-4). (2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings; Vol. 2018-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BIOCAS.2017.8325057
Han, Myungjin ; Ha, Go Eun ; Cheong, Eunji ; Han, Gunhee ; Chae, Youngcheol. / An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA. 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 1-4 (2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings).
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abstract = "A compact area/power efficient electrode-matched neural-spike detector (NSD) is proposed to provide an implantable multi-electrode array (MEA). A correlation scheme with only the input sampling capacitors makes an area reduction, and the recording of neural-spike events enables a power reduction, showing 0.0044 mm 2 and 0.55 μW. Together with proposed NSD, an implantable 256-channel MEA is fabricated. The electrical measurement results show that the NSD achieves an input-referred noise of 10.1 μV rms with 1 kHz to 10 kHz bandwidth, providing NEF/PEF/AEF of 1.71/5.28/0.0044, respectively, and CMRR of 67.5 dB. It shows ×7.5/×1.6 area/power improvements, compared to previous state-of-the-art NSDs. The fabricated implantable MEA is demonstrated by cell-cultured and brain-sliced experiments.",
author = "Myungjin Han and Ha, {Go Eun} and Eunji Cheong and Gunhee Han and Youngcheol Chae",
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Han, M, Ha, GE, Cheong, E, Han, G & Chae, Y 2018, An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA. in 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings. 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings, vol. 2018-January, Institute of Electrical and Electronics Engineers Inc., pp. 1-4, 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017, Torino, Italy, 17/10/19. https://doi.org/10.1109/BIOCAS.2017.8325057

An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA. / Han, Myungjin; Ha, Go Eun; Cheong, Eunji; Han, Gunhee; Chae, Youngcheol.

2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. p. 1-4 (2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings; Vol. 2018-January).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Han M, Ha GE, Cheong E, Han G, Chae Y. An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA. In 2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2018. p. 1-4. (2017 IEEE Biomedical Circuits and Systems Conference, BioCAS 2017 - Proceedings). https://doi.org/10.1109/BIOCAS.2017.8325057