An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING

Yong Hwan Choi, Dong Hyun Kang, Seung Il Yoon, Min Gu Kim, Jaesam Sim, Jongbaeg Kim, Yong Jun Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

An integrated thermoelectric biosensor chip is being proposed for continuous monitoring of biochemical process. It is composed of a preconcentrator and a thermoelectric biosensor. In the preconcentrator, the concentration of the biochemical sample is electrodynamically condensed, which results in enhancement of the sensitivity of the integrated sensor. Then, in the sensor, the preconcentrated target molecules interact with injected capture molecules and generate reaction heat. The reaction heat is detected based on thermoelectric effect with an integrated split-flow micro channel which provides self-compensation of thermal noise. In the fabricated biochip, 95.8% of the sample was concentrated to be 2.88-fold and detected with the sensitivity of 54.7V/molarity in biotin-streptavidin application.

Original languageEnglish
Title of host publication2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011
Pages837-840
Number of pages4
DOIs
Publication statusPublished - 2011 Apr 13
Event24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011 - Cancun, Mexico
Duration: 2011 Jan 232011 Jan 27

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

Other24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011
CountryMexico
CityCancun
Period11/1/2311/1/27

Fingerprint

Electrodynamics
bioinstrumentation
Biosensors
electrodynamics
chips
Thermoelectricity
Biochips
heat
biotin
Molecules
Thermal noise
Streptavidin
sensitivity
sensors
thermal noise
Sensors
Biotin
molecules
augmentation
Monitoring

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Choi, Y. H., Kang, D. H., Yoon, S. I., Kim, M. G., Sim, J., Kim, J., & Kim, Y. J. (2011). An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING. In 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011 (pp. 837-840). [5734555] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2011.5734555
Choi, Yong Hwan ; Kang, Dong Hyun ; Yoon, Seung Il ; Kim, Min Gu ; Sim, Jaesam ; Kim, Jongbaeg ; Kim, Yong Jun. / An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING. 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. 2011. pp. 837-840 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).
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abstract = "An integrated thermoelectric biosensor chip is being proposed for continuous monitoring of biochemical process. It is composed of a preconcentrator and a thermoelectric biosensor. In the preconcentrator, the concentration of the biochemical sample is electrodynamically condensed, which results in enhancement of the sensitivity of the integrated sensor. Then, in the sensor, the preconcentrated target molecules interact with injected capture molecules and generate reaction heat. The reaction heat is detected based on thermoelectric effect with an integrated split-flow micro channel which provides self-compensation of thermal noise. In the fabricated biochip, 95.8{\%} of the sample was concentrated to be 2.88-fold and detected with the sensitivity of 54.7V/molarity in biotin-streptavidin application.",
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Choi, YH, Kang, DH, Yoon, SI, Kim, MG, Sim, J, Kim, J & Kim, YJ 2011, An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING. in 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011., 5734555, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 837-840, 24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011, Cancun, Mexico, 11/1/23. https://doi.org/10.1109/MEMSYS.2011.5734555

An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING. / Choi, Yong Hwan; Kang, Dong Hyun; Yoon, Seung Il; Kim, Min Gu; Sim, Jaesam; Kim, Jongbaeg; Kim, Yong Jun.

2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. 2011. p. 837-840 5734555 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Choi YH, Kang DH, Yoon SI, Kim MG, Sim J, Kim J et al. An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING. In 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. 2011. p. 837-840. 5734555. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2011.5734555