An electrodynmic preconcentrator for application of Lab-on-a-Chip

This research proposes an electrodynamic preconcentrator for continuous biochemical applications. In the preconcentrator, the concentration ofthe injected biochemical solution is electrodynamically condensed. The performance ofthe preconcentrator was evaluated at various flow rates and applied voltages. In order to verify characteristics ofthe device, 10 μm-diameter polystyrene (PS) particles and blood cells were prepared in phosphate buffered saline (PBS) solution. The PS particles were concentrated by applying AC voltage from 0 to 16 V_pp at 3 MHz, and blood cells were concentrated by applying AC voltage from 0 to 10 V_pp at 1 MHz. In the experimental result of PS particles, with approximately 95.8% of concentration efficiency was achieved at an applied voltage of 16 V_pp and a flow rate below 100 μl/h. And, in the experimental result of blood cells, with approximately 92.5% of concentration efficiency was achieved at an applied voltage of 10 V_pp and a flow rate below 0.1 μ1|/m.