An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems

Jae Kyong Kim; So Yeon Bong; Rackhyun Park; Junsoo Park; Doo Ok Jang

doi:10.1016/j.saa.2022.121333

An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems

Jae Kyong Kim, So Yeon Bong, Rackhyun Park, Junsoo Park, Doo Ok Jang

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A probe with an isothiocyanate group was synthesized and evaluated for its H₂S sensing ability. Upon addition of H₂S, the probe exhibited ratiometric properties during absorption with a red-shift. The probe exhibited fluorescent off–on responses towards H₂S via the ESIPT process, due to the conversion of isocyanate into amine. UV–vis, fluorescence, and ¹H NMR spectroscopic analyses were performed to investigate the sensing mechanism. The probe has a large Stokes shift, short response time, and low detection limit. It can be used to estimate H₂S levels within the range of 0–36 nM. The practical applicability of the probe was demonstrated using water samples and living cells.

Original language	English
Article number	121333
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	278
DOIs	https://doi.org/10.1016/j.saa.2022.121333
Publication status	Published - 2022 Oct 5

Bibliographical note

Funding Information:
This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2021R1F1A1061526 ).

Publisher Copyright:
© 2022 Elsevier B.V.

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Atomic and Molecular Physics, and Optics
Instrumentation
Spectroscopy

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10.1016/j.saa.2022.121333

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title = "An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems",

abstract = "A probe with an isothiocyanate group was synthesized and evaluated for its H2S sensing ability. Upon addition of H2S, the probe exhibited ratiometric properties during absorption with a red-shift. The probe exhibited fluorescent off–on responses towards H2S via the ESIPT process, due to the conversion of isocyanate into amine. UV–vis, fluorescence, and 1H NMR spectroscopic analyses were performed to investigate the sensing mechanism. The probe has a large Stokes shift, short response time, and low detection limit. It can be used to estimate H2S levels within the range of 0–36 nM. The practical applicability of the probe was demonstrated using water samples and living cells.",

author = "Kim, {Jae Kyong} and Bong, {So Yeon} and Rackhyun Park and Junsoo Park and Jang, {Doo Ok}",

note = "Funding Information: This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2021R1F1A1061526 ). Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

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doi = "10.1016/j.saa.2022.121333",

language = "English",

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T1 - An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems

AU - Kim, Jae Kyong

AU - Bong, So Yeon

AU - Park, Rackhyun

AU - Park, Junsoo

AU - Jang, Doo Ok

N1 - Funding Information: This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (No. 2021R1F1A1061526 ). Publisher Copyright: © 2022 Elsevier B.V.

PY - 2022/10/5

Y1 - 2022/10/5

N2 - A probe with an isothiocyanate group was synthesized and evaluated for its H2S sensing ability. Upon addition of H2S, the probe exhibited ratiometric properties during absorption with a red-shift. The probe exhibited fluorescent off–on responses towards H2S via the ESIPT process, due to the conversion of isocyanate into amine. UV–vis, fluorescence, and 1H NMR spectroscopic analyses were performed to investigate the sensing mechanism. The probe has a large Stokes shift, short response time, and low detection limit. It can be used to estimate H2S levels within the range of 0–36 nM. The practical applicability of the probe was demonstrated using water samples and living cells.

AB - A probe with an isothiocyanate group was synthesized and evaluated for its H2S sensing ability. Upon addition of H2S, the probe exhibited ratiometric properties during absorption with a red-shift. The probe exhibited fluorescent off–on responses towards H2S via the ESIPT process, due to the conversion of isocyanate into amine. UV–vis, fluorescence, and 1H NMR spectroscopic analyses were performed to investigate the sensing mechanism. The probe has a large Stokes shift, short response time, and low detection limit. It can be used to estimate H2S levels within the range of 0–36 nM. The practical applicability of the probe was demonstrated using water samples and living cells.

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JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

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An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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