An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia

Mun Yong Lee, Yun Sik Choi, Jeong Sun Choi, Do Sik Min, Myung Hoon Chun, Ok Nyu Kim, Sang Bok Lee, Seong Yun Kim

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8 Citations (Scopus)

Abstract

The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalBrain Research
Volume924
Issue number2
DOIs
Publication statusPublished - 2002 Jan 11

Bibliographical note

Funding Information:
The authors thank Mrs. Hee-Duck Rho and Byoung-Ouk Hong for their excellent technical assistance. This research was supported by The Catholic Medical Center Research Foundation established in 2000 (to M.-Y.L. and S.Y.K).

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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