An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia

Mun Yong Lee, Yun Sik Choi, Jeong Sun Choi, Do Sik Min, Myung Hoon Chun, Ok Nyu Kim, Sang Bok Lee, Seong Yun Kim

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalBrain Research
Volume924
Issue number2
DOIs
Publication statusPublished - 2002 Jan 11

Fingerprint

HSP110 Heat-Shock Proteins
Glial Fibrillary Acidic Protein
Prosencephalon
Astrocytes
Fluorescent Antibody Technique
Hippocampus
Ischemia
Neurons
Proteins
rat Hspa4 protein

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Lee, Mun Yong ; Choi, Yun Sik ; Choi, Jeong Sun ; Min, Do Sik ; Chun, Myung Hoon ; Kim, Ok Nyu ; Lee, Sang Bok ; Kim, Seong Yun. / An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia. In: Brain Research. 2002 ; Vol. 924, No. 2. pp. 237-241.
@article{ae93ef8788c34a508fd38c9d4840ec9f,
title = "An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia",
abstract = "The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.",
author = "Lee, {Mun Yong} and Choi, {Yun Sik} and Choi, {Jeong Sun} and Min, {Do Sik} and Chun, {Myung Hoon} and Kim, {Ok Nyu} and Lee, {Sang Bok} and Kim, {Seong Yun}",
year = "2002",
month = "1",
day = "11",
doi = "10.1016/S0006-8993(01)03295-4",
language = "English",
volume = "924",
pages = "237--241",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "2",

}

An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia. / Lee, Mun Yong; Choi, Yun Sik; Choi, Jeong Sun; Min, Do Sik; Chun, Myung Hoon; Kim, Ok Nyu; Lee, Sang Bok; Kim, Seong Yun.

In: Brain Research, Vol. 924, No. 2, 11.01.2002, p. 237-241.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia

AU - Lee, Mun Yong

AU - Choi, Yun Sik

AU - Choi, Jeong Sun

AU - Min, Do Sik

AU - Chun, Myung Hoon

AU - Kim, Ok Nyu

AU - Lee, Sang Bok

AU - Kim, Seong Yun

PY - 2002/1/11

Y1 - 2002/1/11

N2 - The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

AB - The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

UR - http://www.scopus.com/inward/record.url?scp=0037059605&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037059605&partnerID=8YFLogxK

U2 - 10.1016/S0006-8993(01)03295-4

DO - 10.1016/S0006-8993(01)03295-4

M3 - Article

C2 - 11750909

AN - SCOPUS:0037059605

VL - 924

SP - 237

EP - 241

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 2

ER -