An implantable wireless optogenetic stimulation system for peripheral nerve control

Kang Il Song, Sunghee E. Park, Myoung Soo Kim, Chulmin Joo, Yong-Jun Kim, Jun Kyo F. Suh, Do Sik Hwang, Inchan Youn

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.

Original languageEnglish
Title of host publication2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1033-1036
Number of pages4
ISBN (Electronic)9781424492718
DOIs
Publication statusPublished - 2015 Nov 4
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: 2015 Aug 252015 Aug 29

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2015-November
ISSN (Print)1557-170X

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
CountryItaly
CityMilan
Period15/8/2515/8/29

Fingerprint

Optogenetics
Peripheral Nerves
Electrodes
Communication
Sciatic Nerve
Communication systems
Implanted Electrodes
Ankle
Transgenic Mice
Polydimethylsiloxane
Light emitting diodes
Controllers

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Cite this

Song, K. I., Park, S. E., Kim, M. S., Joo, C., Kim, Y-J., Suh, J. K. F., ... Youn, I. (2015). An implantable wireless optogenetic stimulation system for peripheral nerve control. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (pp. 1033-1036). [7318541] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7318541
Song, Kang Il ; Park, Sunghee E. ; Kim, Myoung Soo ; Joo, Chulmin ; Kim, Yong-Jun ; Suh, Jun Kyo F. ; Hwang, Do Sik ; Youn, Inchan. / An implantable wireless optogenetic stimulation system for peripheral nerve control. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 1033-1036 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).
@inproceedings{6c84149b90f945fea363771be099e1e1,
title = "An implantable wireless optogenetic stimulation system for peripheral nerve control",
abstract = "An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.",
author = "Song, {Kang Il} and Park, {Sunghee E.} and Kim, {Myoung Soo} and Chulmin Joo and Yong-Jun Kim and Suh, {Jun Kyo F.} and Hwang, {Do Sik} and Inchan Youn",
year = "2015",
month = "11",
day = "4",
doi = "10.1109/EMBC.2015.7318541",
language = "English",
series = "Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "1033--1036",
booktitle = "2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015",
address = "United States",

}

Song, KI, Park, SE, Kim, MS, Joo, C, Kim, Y-J, Suh, JKF, Hwang, DS & Youn, I 2015, An implantable wireless optogenetic stimulation system for peripheral nerve control. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015., 7318541, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2015-November, Institute of Electrical and Electronics Engineers Inc., pp. 1033-1036, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 15/8/25. https://doi.org/10.1109/EMBC.2015.7318541

An implantable wireless optogenetic stimulation system for peripheral nerve control. / Song, Kang Il; Park, Sunghee E.; Kim, Myoung Soo; Joo, Chulmin; Kim, Yong-Jun; Suh, Jun Kyo F.; Hwang, Do Sik; Youn, Inchan.

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 1033-1036 7318541 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - An implantable wireless optogenetic stimulation system for peripheral nerve control

AU - Song, Kang Il

AU - Park, Sunghee E.

AU - Kim, Myoung Soo

AU - Joo, Chulmin

AU - Kim, Yong-Jun

AU - Suh, Jun Kyo F.

AU - Hwang, Do Sik

AU - Youn, Inchan

PY - 2015/11/4

Y1 - 2015/11/4

N2 - An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.

AB - An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.

UR - http://www.scopus.com/inward/record.url?scp=84953223721&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84953223721&partnerID=8YFLogxK

U2 - 10.1109/EMBC.2015.7318541

DO - 10.1109/EMBC.2015.7318541

M3 - Conference contribution

C2 - 26736441

AN - SCOPUS:84953223721

T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

SP - 1033

EP - 1036

BT - 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015

PB - Institute of Electrical and Electronics Engineers Inc.

ER -

Song KI, Park SE, Kim MS, Joo C, Kim Y-J, Suh JKF et al. An implantable wireless optogenetic stimulation system for peripheral nerve control. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 1033-1036. 7318541. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2015.7318541