An imported case of Brucella melitensis infection in South Korea

Jee Young Lee, Yongduk Jeon, Mi Young Ahn, Hea Won Ann, In Young Jung, Wooyong Jung, Moo Hyun Kim, Jin Young Ahn, Je Eun Song, Yong Chan Kim, Dong Hyun Oh, Eun Jin Kim, Su Jin Jeong, Nam Su Ku, Hyunsoo Kim, Kyungwon Lee, June Myung Kim, Jun Yong Choi

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Brucellosis is a zoonotic infection that is usually transmitted from cattle to humans through ingestion of animal milk, direct contact with animal parts, or inhalation of aerosolized particles. In Korea, brucellosis seem to be transmitted through close contact with blood, fetus, urine, and placenta of domestic cow that has been infected by Brucella abortus, or inhalation of B. arbortus while examining or slaughtering cow. Brucella melitensis infection is rare in Korea and there have been no reported cases of B. melitensis originating from other countries until now. This report details a case of complicated brucellosis with infective spondylitis in a 48-year-old male construction worker recently returned from Iraq. Infection with B. melitensis was confirmed using 16s rRNA sequencing and omp31 gene analysis. The patient was successfully treated using a combination of rifampin, doxycycline, and streptomycin, in accordance with WHO guidelines. This is the first reported case of complicated brucellosis with infective spondylitis in Korea caused by B. melitensis originating from Iraq.

Original languageEnglish
Pages (from-to)149-152
Number of pages4
JournalInfection and Chemotherapy
Issue number2
Publication statusPublished - 2018 Jun 1

Bibliographical note

Funding Information:
This work was supported by BioNano Health-Guard Research Center funded by the Ministry of Science, ICT, and Future Planning of Korea as a Global Frontier Project (Grant H-GUARD_2013M3A6B2078953), and a grant from the Ministry of Health & Welfare, Republic of Korea (grant number: HI14C1324).

Publisher Copyright:
© 2018 by The Korean Society of Infectious Diseases.

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Pharmacology (medical)


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