An overview of eosinophilic esophagitis

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Eosinophilic esophagitis (EoE) is a chronic, immune/antigenmediated esophageal disease affecting both children and adults. The condition is characterized by an eosinophilic infiltration of the esophageal epithelium. Symptoms of esophageal dysfunction include dysphagia, food impaction and symptoms mimicking gastroesophageal reflux disease. Endoscopic examination typically reveals mucosal fragility, ring or corrugated mucosa, longitudinal furrows, whitish plaques or a small caliber esophagus. Histologic findings of >15 eosinophils per high-power field is the diagnostic hallmark of EoE. An elimination diet, topical corticosteroids or endoscopic dilation for fibrostenotic disease serve as effective therapeutic option.

Original languageEnglish
Pages (from-to)590-597
Number of pages8
JournalGut and liver
Volume8
Issue number6
DOIs
Publication statusPublished - 2014 Nov 1

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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