Analysis and utilization of Joule heating in an electromagnet integrated microfluidic device for biological applications

Suk Heung Song, Bong Seop Kwak, Hyo Il Jung

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Joule heating in the electromagnetic cell sorting system is problematic. Our micro-device was fabricated for the rapid separation by high magnetic field gradients of electromagnet and dissipates the Joule heat energy that causes unnecessary heat-up in the device. By using a cooling channel embedded in microfluidic channel, Joule heat can be reduced to dissipate thermal energy to an active area of a microfluidic channel and maintain the temperature of device biocompatible, e.g. 37 °C. We analyzed the temperature distribution of the device using numerical model and compared with the experimental data. Finally, we demonstrated the magnetic beads separation and obtained the separation efficiency of 97%.

Original languageEnglish
Pages (from-to)e287-e290
JournalCurrent Applied Physics
Volume9
Issue number4 SUPPL.
DOIs
Publication statusPublished - 2009 Jul

Bibliographical note

Funding Information:
This work was supported by National Core Research Center (NCRC) for Nanomedical Technology from the Korea Science & Engineering Foundation (Grant No. R15-2004-024-01001-0), Seoul Research & Business Development (Seoul R&BD Program, 10816), in part by the Grant (20070501-034-006-009-03-00) from BioGreen21 Program, Rural Development Administration, Republic of Korea.

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Physics and Astronomy(all)

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