Abstract
Joule heating in the electromagnetic cell sorting system is problematic. Our micro-device was fabricated for the rapid separation by high magnetic field gradients of electromagnet and dissipates the Joule heat energy that causes unnecessary heat-up in the device. By using a cooling channel embedded in microfluidic channel, Joule heat can be reduced to dissipate thermal energy to an active area of a microfluidic channel and maintain the temperature of device biocompatible, e.g. 37 °C. We analyzed the temperature distribution of the device using numerical model and compared with the experimental data. Finally, we demonstrated the magnetic beads separation and obtained the separation efficiency of 97%.
| Original language | English |
|---|---|
| Journal | Current Applied Physics |
| Volume | 9 |
| Issue number | 4 SUPPL. |
| DOIs | |
| Publication status | Published - 2009 Jul 1 |
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All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Physics and Astronomy(all)
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Analysis and utilization of Joule heating in an electromagnet integrated microfluidic device for biological applications. / Song, Suk Heung; Kwak, Bong Seop; Jung, Hyo il.
In: Current Applied Physics, Vol. 9, No. 4 SUPPL., 01.07.2009.Research output: Contribution to journal › Article
TY - JOUR
T1 - Analysis and utilization of Joule heating in an electromagnet integrated microfluidic device for biological applications
AU - Song, Suk Heung
AU - Kwak, Bong Seop
AU - Jung, Hyo il
PY - 2009/7/1
Y1 - 2009/7/1
N2 - Joule heating in the electromagnetic cell sorting system is problematic. Our micro-device was fabricated for the rapid separation by high magnetic field gradients of electromagnet and dissipates the Joule heat energy that causes unnecessary heat-up in the device. By using a cooling channel embedded in microfluidic channel, Joule heat can be reduced to dissipate thermal energy to an active area of a microfluidic channel and maintain the temperature of device biocompatible, e.g. 37 °C. We analyzed the temperature distribution of the device using numerical model and compared with the experimental data. Finally, we demonstrated the magnetic beads separation and obtained the separation efficiency of 97%.
AB - Joule heating in the electromagnetic cell sorting system is problematic. Our micro-device was fabricated for the rapid separation by high magnetic field gradients of electromagnet and dissipates the Joule heat energy that causes unnecessary heat-up in the device. By using a cooling channel embedded in microfluidic channel, Joule heat can be reduced to dissipate thermal energy to an active area of a microfluidic channel and maintain the temperature of device biocompatible, e.g. 37 °C. We analyzed the temperature distribution of the device using numerical model and compared with the experimental data. Finally, we demonstrated the magnetic beads separation and obtained the separation efficiency of 97%.
UR - http://www.scopus.com/inward/record.url?scp=71849107492&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=71849107492&partnerID=8YFLogxK
U2 - 10.1016/j.cap.2009.06.023
DO - 10.1016/j.cap.2009.06.023
M3 - Article
VL - 9
JO - Current Applied Physics
JF - Current Applied Physics
SN - 1567-1739
IS - 4 SUPPL.
ER -