Abstract
Surface plasmon represents oscillations of electrons at the interface between metal and dielectric layers. Surface plasmon resonance (SPR) is influenced by the environment near the surface, which has been the basis for label-free biosensor structure for various applications of molecular detection. An important aspect of SPR biosensing is that its characteristics are affected by the geometrical structure. Yet most research has focused largely on a structure using flat surface. Although flat structure is suitable for typical sensor applications, it may not be appropriate for wearable or in vivo applications. In this study, we analyzed the effects of surface curvature on flexible SPR biosensors. Curved surface was approximated using a segmented model in which each segment is treated as a flat surface with a different incident angle and then optical characteristics of the overall model were calculated by rigorous coupled wave analysis in two different configurations of light incidence. We calculated curvature effects on SPR with curvature radius larger than 255 μm. It was found that regardless of the incident configurations, resonance curves tend to broaden with increased curvature due to larger momentum dispersion. Resonance shifts as a result of DNA immobilization and hybridization decrease with curvature. The analysis was extended to multi-curvature structure and finds significant fluctuation of resonance shift for parallel light incidence. The study can be of profound importance for plasmonic devices using flexible substrates.
| Original language | English |
|---|---|
| Title of host publication | Plasmonics in Biology and Medicine XIV |
| Editors | Tuan Vo-Dinh, Joseph R. Lakowicz |
| Publisher | SPIE |
| Volume | 10080 |
| ISBN (Electronic) | 9781510606012 |
| DOIs | |
| Publication status | Published - 2017 Jan 1 |
| Event | Plasmonics in Biology and Medicine XIV - San Francisco, United States Duration: 2017 Jan 30 → … |
Other
| Other | Plasmonics in Biology and Medicine XIV |
|---|---|
| Country | United States |
| City | San Francisco |
| Period | 17/1/30 → … |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
Cite this
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Analysis of curvature effects on plasmon biosensing of molecular interactions. / Lee, Hyunwoong; Kim, Donghyun.
Plasmonics in Biology and Medicine XIV. ed. / Tuan Vo-Dinh; Joseph R. Lakowicz. Vol. 10080 SPIE, 2017. 100800O.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - Analysis of curvature effects on plasmon biosensing of molecular interactions
AU - Lee, Hyunwoong
AU - Kim, Donghyun
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Surface plasmon represents oscillations of electrons at the interface between metal and dielectric layers. Surface plasmon resonance (SPR) is influenced by the environment near the surface, which has been the basis for label-free biosensor structure for various applications of molecular detection. An important aspect of SPR biosensing is that its characteristics are affected by the geometrical structure. Yet most research has focused largely on a structure using flat surface. Although flat structure is suitable for typical sensor applications, it may not be appropriate for wearable or in vivo applications. In this study, we analyzed the effects of surface curvature on flexible SPR biosensors. Curved surface was approximated using a segmented model in which each segment is treated as a flat surface with a different incident angle and then optical characteristics of the overall model were calculated by rigorous coupled wave analysis in two different configurations of light incidence. We calculated curvature effects on SPR with curvature radius larger than 255 μm. It was found that regardless of the incident configurations, resonance curves tend to broaden with increased curvature due to larger momentum dispersion. Resonance shifts as a result of DNA immobilization and hybridization decrease with curvature. The analysis was extended to multi-curvature structure and finds significant fluctuation of resonance shift for parallel light incidence. The study can be of profound importance for plasmonic devices using flexible substrates.
AB - Surface plasmon represents oscillations of electrons at the interface between metal and dielectric layers. Surface plasmon resonance (SPR) is influenced by the environment near the surface, which has been the basis for label-free biosensor structure for various applications of molecular detection. An important aspect of SPR biosensing is that its characteristics are affected by the geometrical structure. Yet most research has focused largely on a structure using flat surface. Although flat structure is suitable for typical sensor applications, it may not be appropriate for wearable or in vivo applications. In this study, we analyzed the effects of surface curvature on flexible SPR biosensors. Curved surface was approximated using a segmented model in which each segment is treated as a flat surface with a different incident angle and then optical characteristics of the overall model were calculated by rigorous coupled wave analysis in two different configurations of light incidence. We calculated curvature effects on SPR with curvature radius larger than 255 μm. It was found that regardless of the incident configurations, resonance curves tend to broaden with increased curvature due to larger momentum dispersion. Resonance shifts as a result of DNA immobilization and hybridization decrease with curvature. The analysis was extended to multi-curvature structure and finds significant fluctuation of resonance shift for parallel light incidence. The study can be of profound importance for plasmonic devices using flexible substrates.
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U2 - 10.1117/12.2250684
DO - 10.1117/12.2250684
M3 - Conference contribution
AN - SCOPUS:85019264648
VL - 10080
BT - Plasmonics in Biology and Medicine XIV
A2 - Vo-Dinh, Tuan
A2 - Lakowicz, Joseph R.
PB - SPIE
ER -