Anaphylaxis to venom of the Pachycondyla species ant

Yeong Yeon Yun, Si Hwan Ko, Jungwon Park, Chein Soo Hong

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background: In the southeastern United States, imported fire ants have caused systemic reactions with a high incidence. On the contrary, in Korea Pachycondyla species ants (P chinensis and P solitaria), and the family Formicidae, which are in the genus Pachycondyla and the subfamily Ponerinae, have only occasionally caused systemic reactions. Objective: We sought to assess whether commercially available imported fire ant extract would be useful in treating patients with anaphylaxis induced by venom from a Pachycondyla species ant. Methods: Serum samples were collected from 2 women who had anaphylaxis induced by Pachycondyla species ant venom and from 6 volunteers with no history of having been stung. Specific IgE to Pachycondyla species ant extracts was measured by means of ELISA and possible allergenic components by immunoblot. Cross-reactivity between Pachycondyla chinensis, P solitaria, and imported fire ant extracts was also measured by inhibitory ELISA. Results: Skin prick test responses were strongly positive to the extract of P chinensis (1:20 wt/vol) in the patient. Ten healthy volunteers exhibited negative responses. The 2 patients' sera exhibited high ELISA values, with absorbencies of 0.78 and 0.61 for P chinensis and 0.83 and 0.68 for P solitaria, respectively, and negative ELISA values for the extract of imported fire ants (absorbency <0.01). Imported fire ants showed no inhibition of the IgE binding to P chinensis or P solitaria. Possible allergenic components of Pachycondyla species ant extracts are 29- and 27-kd proteins and, less frequently, 16 kd proteins. Conclusion: Our data suggest that patients who have had an anaphylactic reaction to a Pachycondyla species ant might not benefit from immunotherapy with an imported fire ant extract. Immunotherapy with the extract of Pachycondyla species ants is expected to be highly effective.

Original languageEnglish
Pages (from-to)879-882
Number of pages4
JournalJournal of Allergy and Clinical Immunology
Volume104
Issue number4 I
DOIs
Publication statusPublished - 1999 Jan 1

Fingerprint

Ants
Venoms
Anaphylaxis
Enzyme-Linked Immunosorbent Assay
Immunotherapy
Immunoglobulin E
Ant Venoms
Southeastern United States
Korea
Skin Tests
Serum
Volunteers
Healthy Volunteers
Proteins

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

Cite this

Yun, Yeong Yeon ; Ko, Si Hwan ; Park, Jungwon ; Hong, Chein Soo. / Anaphylaxis to venom of the Pachycondyla species ant. In: Journal of Allergy and Clinical Immunology. 1999 ; Vol. 104, No. 4 I. pp. 879-882.
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Anaphylaxis to venom of the Pachycondyla species ant. / Yun, Yeong Yeon; Ko, Si Hwan; Park, Jungwon; Hong, Chein Soo.

In: Journal of Allergy and Clinical Immunology, Vol. 104, No. 4 I, 01.01.1999, p. 879-882.

Research output: Contribution to journalArticle

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