Anchored proteinase-targetable optomagnetic nanoprobes for molecular imaging of invasive cancer cells

Joseph Park, Jaemoon Yang, Eun Kyung Lim, Eunjung Kim, Jihye Choi, Joo Kyung Ryu, Nam Hee Kim, Jinsuck Suh, Jong In Yook, yongmin Huh, Seungjoo Haam

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Activatable nanoprobe: A dual-function nanoprobe has been developed that detects membrane type 1-matrix metalloproteinase (MT1-MMP) activity by a dual-signal increase in complementary fluorescence imaging (FI) and magnetic resonance imaging (MRI). MNCs=magnetic nanocrystals, Q=quencher, F=fluorescence dye.

Original languageEnglish
Pages (from-to)945-948
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number4
DOIs
Publication statusPublished - 2012 Jan 23

Fingerprint

Nanoprobes
Molecular imaging
Peptide Hydrolases
Fluorescence
Cells
Matrix Metalloproteinase 14
Imaging techniques
Magnetic resonance
Nanocrystals
Coloring Agents
Dyes
Membranes
Metalloproteases

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

Park, Joseph ; Yang, Jaemoon ; Lim, Eun Kyung ; Kim, Eunjung ; Choi, Jihye ; Ryu, Joo Kyung ; Kim, Nam Hee ; Suh, Jinsuck ; Yook, Jong In ; Huh, yongmin ; Haam, Seungjoo. / Anchored proteinase-targetable optomagnetic nanoprobes for molecular imaging of invasive cancer cells. In: Angewandte Chemie - International Edition. 2012 ; Vol. 51, No. 4. pp. 945-948.
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Anchored proteinase-targetable optomagnetic nanoprobes for molecular imaging of invasive cancer cells. / Park, Joseph; Yang, Jaemoon; Lim, Eun Kyung; Kim, Eunjung; Choi, Jihye; Ryu, Joo Kyung; Kim, Nam Hee; Suh, Jinsuck; Yook, Jong In; Huh, yongmin; Haam, Seungjoo.

In: Angewandte Chemie - International Edition, Vol. 51, No. 4, 23.01.2012, p. 945-948.

Research output: Contribution to journalArticle

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AU - Ryu, Joo Kyung

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AU - Suh, Jinsuck

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AU - Huh, yongmin

AU - Haam, Seungjoo

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