Anesthetic considerations for laparoscopy for rectal cancer in patient with amyotrophic lateral sclerosis: A case report

Bo Ra Kim, Young Bok Lee, Su Jin Kim, Young Wan Kim

Research output: Contribution to journalArticle

Abstract

Amyotrophic lateral sclerosis, which is also known as motor neuron disease, is a chronic neurodegenerative disease characterized by progressive muscular weakness, respiratory muscle disability, and eventual death. Previous epidemiologic studies have shown no association between cancer and amyotrophic lateral sclerosis. Colorectal cancer arising in patients with amyotrophic lateral sclerosis has rarely been reported. Here, we report a case involving rectal cancer arising in a patient with amyotrophic lateral sclerosis who subsequently underwent curative laparoscopic surgery and adjuvant chemotherapy. Amyotrophic lateral sclerosis causes the deterioration of respiratory function by compromising expiratory and inspiratory muscles; accordingly, patients with amyotrophic lateral sclerosis are at high anesthetic risk, especially with respect to general anesthesia. Careful airway management is essential, and intraoperative neuromuscular monitoring is important. A depolarizing muscle relaxant such as succinylcholine should not be used because of the potential risk of developing hyperkalemia or rhabdomyolysis. Thus, a nondepolarizing muscle relaxant (rocuronium) was used at a low dose in this case. In addition, fentanyl for postoperative patient-controlled analgesia should be used cautiously because fentanyl can cause respiratory muscle rigidity, which may reduce postoperative respiratory function in patients with amyotrophic lateral sclerosis.

Original languageEnglish
Pages (from-to)175-176
Number of pages2
JournalEgyptian Journal of Anaesthesia
Volume34
Issue number4
DOIs
Publication statusPublished - 2018 Oct

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Amyotrophic Lateral Sclerosis
Rectal Neoplasms
Laparoscopy
Anesthetics
Respiratory Muscles
Fentanyl
Neuromuscular Depolarizing Agents
Neuromuscular Monitoring
Muscle Rigidity
Intraoperative Monitoring
Patient-Controlled Analgesia
Muscles
Motor Neuron Disease
Hyperkalemia
Rhabdomyolysis
Succinylcholine
Airway Management
Muscle Weakness
Adjuvant Chemotherapy
Neurodegenerative Diseases

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

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abstract = "Amyotrophic lateral sclerosis, which is also known as motor neuron disease, is a chronic neurodegenerative disease characterized by progressive muscular weakness, respiratory muscle disability, and eventual death. Previous epidemiologic studies have shown no association between cancer and amyotrophic lateral sclerosis. Colorectal cancer arising in patients with amyotrophic lateral sclerosis has rarely been reported. Here, we report a case involving rectal cancer arising in a patient with amyotrophic lateral sclerosis who subsequently underwent curative laparoscopic surgery and adjuvant chemotherapy. Amyotrophic lateral sclerosis causes the deterioration of respiratory function by compromising expiratory and inspiratory muscles; accordingly, patients with amyotrophic lateral sclerosis are at high anesthetic risk, especially with respect to general anesthesia. Careful airway management is essential, and intraoperative neuromuscular monitoring is important. A depolarizing muscle relaxant such as succinylcholine should not be used because of the potential risk of developing hyperkalemia or rhabdomyolysis. Thus, a nondepolarizing muscle relaxant (rocuronium) was used at a low dose in this case. In addition, fentanyl for postoperative patient-controlled analgesia should be used cautiously because fentanyl can cause respiratory muscle rigidity, which may reduce postoperative respiratory function in patients with amyotrophic lateral sclerosis.",
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Anesthetic considerations for laparoscopy for rectal cancer in patient with amyotrophic lateral sclerosis : A case report. / Kim, Bo Ra; Lee, Young Bok; Kim, Su Jin; Kim, Young Wan.

In: Egyptian Journal of Anaesthesia, Vol. 34, No. 4, 10.2018, p. 175-176.

Research output: Contribution to journalArticle

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