Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: From the poststent optimal stent expansion trial

Sang Min Park; Jung Sun Kim; Young Guk Ko; Donghoon Choi; Myeong Ki Hong; Yangsoo Jang; Woong Chol Kang; Taehoon Ahn; Byoung Keuk Kim; Seong Jin Oh; Dong Woon Jeon; Joo Young Yang

doi:10.1002/ccd.22635

Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: From the poststent optimal stent expansion trial

Sang Min Park, Jung Sun Kim, Young Guk Ko, Donghoon Choi, Myeong Ki Hong, Yangsoo Jang, Woong Chol Kang, Taehoon Ahn, Byoung Keuk Kim, Seong Jin Oh, Dong Woon Jeon, Joo Young Yang

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Objectives: The aims of this study were to identify the efficacy of optimal stent expansion (OSE) according to the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study) criteria in drug-eluting stent (DES) and compare paclitaxel-eluting stent (PES) to sirolimus-eluting stent (SES). Background: Although poststent high-pressure balloon dilatation is proposed after bare metal stent implantation according to OSE, defined by the criteria of the MUSIC Study, very little data are available in DES. Methods: Two hundred fifty patients (M:F = 149:101; age, 61.5 ± 9.2 years) who underwent 9-month follow-up angiography in the Poststent Optimal Stent Expansion Trial (POET) were included in this study. We assessed angiographic in-stent restenosis (ISR) and neointima volume (NV) using IVUS at 9 months. Results: At 9-month follow up, there were no significant differences in ISR and NV index (NV/stent length, mm²) between patients with and without OSE. However, the rate of ISR and NV index were higher in PES [ISR: 18 (13.7%) and 4 (3.4%), P = 0.004; NV index: 1.02 ± 0.99 mm² and 0.21 ± 0.37, P < 0.001 in PES and SES]. Conclusions: OSE according to the MUSIC Study criteria was not related to ISR and NV in the DES era but PES had a significantly higher ISR rate and NV than SES after poststent high-pressure balloon dilatation.

Original language	English
Pages (from-to)	15-21
Number of pages	7
Journal	Catheterization and Cardiovascular Interventions
Volume	77
Issue number	1
DOIs	https://doi.org/10.1002/ccd.22635
Publication status	Published - 2011 Jan 1

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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Park, S. M., Kim, J. S., Ko, Y. G., Choi, D., Hong, M. K., Jang, Y., Kang, W. C., Ahn, T., Kim, B. K., Oh, S. J., Jeon, D. W., & Yang, J. Y. (2011). Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: From the poststent optimal stent expansion trial. Catheterization and Cardiovascular Interventions, 77(1), 15-21. https://doi.org/10.1002/ccd.22635

Park, Sang Min ; Kim, Jung Sun ; Ko, Young Guk ; Choi, Donghoon ; Hong, Myeong Ki ; Jang, Yangsoo ; Kang, Woong Chol ; Ahn, Taehoon ; Kim, Byoung Keuk ; Oh, Seong Jin ; Jeon, Dong Woon ; Yang, Joo Young. / Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation : From the poststent optimal stent expansion trial. In: Catheterization and Cardiovascular Interventions. 2011 ; Vol. 77, No. 1. pp. 15-21.

@article{6622ff1519c945549973ff9b231d55a5,

title = "Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: From the poststent optimal stent expansion trial",

abstract = "Objectives: The aims of this study were to identify the efficacy of optimal stent expansion (OSE) according to the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study) criteria in drug-eluting stent (DES) and compare paclitaxel-eluting stent (PES) to sirolimus-eluting stent (SES). Background: Although poststent high-pressure balloon dilatation is proposed after bare metal stent implantation according to OSE, defined by the criteria of the MUSIC Study, very little data are available in DES. Methods: Two hundred fifty patients (M:F = 149:101; age, 61.5 ± 9.2 years) who underwent 9-month follow-up angiography in the Poststent Optimal Stent Expansion Trial (POET) were included in this study. We assessed angiographic in-stent restenosis (ISR) and neointima volume (NV) using IVUS at 9 months. Results: At 9-month follow up, there were no significant differences in ISR and NV index (NV/stent length, mm2) between patients with and without OSE. However, the rate of ISR and NV index were higher in PES [ISR: 18 (13.7%) and 4 (3.4%), P = 0.004; NV index: 1.02 ± 0.99 mm2 and 0.21 ± 0.37, P < 0.001 in PES and SES]. Conclusions: OSE according to the MUSIC Study criteria was not related to ISR and NV in the DES era but PES had a significantly higher ISR rate and NV than SES after poststent high-pressure balloon dilatation.",

author = "Park, {Sang Min} and Kim, {Jung Sun} and Ko, {Young Guk} and Donghoon Choi and Hong, {Myeong Ki} and Yangsoo Jang and Kang, {Woong Chol} and Taehoon Ahn and Kim, {Byoung Keuk} and Oh, {Seong Jin} and Jeon, {Dong Woon} and Yang, {Joo Young}",

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Park, SM, Kim, JS, Ko, YG, Choi, D , Hong, MK , Jang, Y, Kang, WC, Ahn, T, Kim, BK, Oh, SJ, Jeon, DW & Yang, JY 2011, 'Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: From the poststent optimal stent expansion trial', Catheterization and Cardiovascular Interventions, vol. 77, no. 1, pp. 15-21. https://doi.org/10.1002/ccd.22635

Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation : From the poststent optimal stent expansion trial. / Park, Sang Min; Kim, Jung Sun; Ko, Young Guk; Choi, Donghoon ; Hong, Myeong Ki ; Jang, Yangsoo; Kang, Woong Chol; Ahn, Taehoon; Kim, Byoung Keuk; Oh, Seong Jin; Jeon, Dong Woon; Yang, Joo Young.

In: Catheterization and Cardiovascular Interventions, Vol. 77, No. 1, 01.01.2011, p. 15-21.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation

T2 - From the poststent optimal stent expansion trial

AU - Park, Sang Min

AU - Kim, Jung Sun

AU - Ko, Young Guk

AU - Choi, Donghoon

AU - Hong, Myeong Ki

AU - Jang, Yangsoo

AU - Kang, Woong Chol

AU - Ahn, Taehoon

AU - Kim, Byoung Keuk

AU - Oh, Seong Jin

AU - Jeon, Dong Woon

AU - Yang, Joo Young

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Objectives: The aims of this study were to identify the efficacy of optimal stent expansion (OSE) according to the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study) criteria in drug-eluting stent (DES) and compare paclitaxel-eluting stent (PES) to sirolimus-eluting stent (SES). Background: Although poststent high-pressure balloon dilatation is proposed after bare metal stent implantation according to OSE, defined by the criteria of the MUSIC Study, very little data are available in DES. Methods: Two hundred fifty patients (M:F = 149:101; age, 61.5 ± 9.2 years) who underwent 9-month follow-up angiography in the Poststent Optimal Stent Expansion Trial (POET) were included in this study. We assessed angiographic in-stent restenosis (ISR) and neointima volume (NV) using IVUS at 9 months. Results: At 9-month follow up, there were no significant differences in ISR and NV index (NV/stent length, mm2) between patients with and without OSE. However, the rate of ISR and NV index were higher in PES [ISR: 18 (13.7%) and 4 (3.4%), P = 0.004; NV index: 1.02 ± 0.99 mm2 and 0.21 ± 0.37, P < 0.001 in PES and SES]. Conclusions: OSE according to the MUSIC Study criteria was not related to ISR and NV in the DES era but PES had a significantly higher ISR rate and NV than SES after poststent high-pressure balloon dilatation.

AB - Objectives: The aims of this study were to identify the efficacy of optimal stent expansion (OSE) according to the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study) criteria in drug-eluting stent (DES) and compare paclitaxel-eluting stent (PES) to sirolimus-eluting stent (SES). Background: Although poststent high-pressure balloon dilatation is proposed after bare metal stent implantation according to OSE, defined by the criteria of the MUSIC Study, very little data are available in DES. Methods: Two hundred fifty patients (M:F = 149:101; age, 61.5 ± 9.2 years) who underwent 9-month follow-up angiography in the Poststent Optimal Stent Expansion Trial (POET) were included in this study. We assessed angiographic in-stent restenosis (ISR) and neointima volume (NV) using IVUS at 9 months. Results: At 9-month follow up, there were no significant differences in ISR and NV index (NV/stent length, mm2) between patients with and without OSE. However, the rate of ISR and NV index were higher in PES [ISR: 18 (13.7%) and 4 (3.4%), P = 0.004; NV index: 1.02 ± 0.99 mm2 and 0.21 ± 0.37, P < 0.001 in PES and SES]. Conclusions: OSE according to the MUSIC Study criteria was not related to ISR and NV in the DES era but PES had a significantly higher ISR rate and NV than SES after poststent high-pressure balloon dilatation.

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