Anorectal dysfunction in systemic sclerosis

Kyung Chul Kim, Hyo Jin Park, Soo Kon Lee, Jun Pyo Chung, Kwan Sik Lee, Chae Yoon Chon, In Suh Park

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This study was aimed to evaluate the anorectal dysfunction in systemic sclerosis(SSc) and propose the clinical significance of anorectal manometry in patients with SSc. Seven patients with SSc were evaluated with manometry for anorectal function and an additional 11 normal subjects were collected as a control group. The study group underwent esophageal manometry as well and the correlation between the degree of anorectal and esophageal dysfunction was evaluated. Patients showed a lower tolerance for balloon distention of the rectum than controls(minimal sensory volume and urgency volume, P<0.05). The resting and squeezing pressure of the anal sphincter and the functional length of the anal canal showed no significant difference in these two groups. Rectoanal inhibitory reflex was absent in one(14%) and diminished in two(29%) of seven patients with SSc. SSc patients also showed abnormal esophageal manometry findings, notably decreased LES pressure and body amplitude of distal 2/3 esophagus. The comparision between manometric profiles of anorectum and esophagus showed no significant correlation by statistical analysis. In conclusion, our data could suggest that anorectal function may be impaired in patients with SSc which could reflect the involvement of the anorectum by the disease, and that anorectal manometric studies can be useful to detect such dysfunction in patients with SSc, even before clinical symptoms.

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalJournal of Korean medical science
Volume11
Issue number3
DOIs
Publication statusPublished - 1996 Jan 1

Fingerprint

Systemic Scleroderma
Manometry
Anal Canal
Esophagus
Rectal Diseases
Pressure
Abnormal Reflexes
Rectum
Control Groups

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, K. C., Park, H. J., Lee, S. K., Chung, J. P., Lee, K. S., Chon, C. Y., & Park, I. S. (1996). Anorectal dysfunction in systemic sclerosis. Journal of Korean medical science, 11(3), 244-249. https://doi.org/10.3346/jkms.1996.11.3.244
Kim, Kyung Chul ; Park, Hyo Jin ; Lee, Soo Kon ; Chung, Jun Pyo ; Lee, Kwan Sik ; Chon, Chae Yoon ; Park, In Suh. / Anorectal dysfunction in systemic sclerosis. In: Journal of Korean medical science. 1996 ; Vol. 11, No. 3. pp. 244-249.
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abstract = "This study was aimed to evaluate the anorectal dysfunction in systemic sclerosis(SSc) and propose the clinical significance of anorectal manometry in patients with SSc. Seven patients with SSc were evaluated with manometry for anorectal function and an additional 11 normal subjects were collected as a control group. The study group underwent esophageal manometry as well and the correlation between the degree of anorectal and esophageal dysfunction was evaluated. Patients showed a lower tolerance for balloon distention of the rectum than controls(minimal sensory volume and urgency volume, P<0.05). The resting and squeezing pressure of the anal sphincter and the functional length of the anal canal showed no significant difference in these two groups. Rectoanal inhibitory reflex was absent in one(14{\%}) and diminished in two(29{\%}) of seven patients with SSc. SSc patients also showed abnormal esophageal manometry findings, notably decreased LES pressure and body amplitude of distal 2/3 esophagus. The comparision between manometric profiles of anorectum and esophagus showed no significant correlation by statistical analysis. In conclusion, our data could suggest that anorectal function may be impaired in patients with SSc which could reflect the involvement of the anorectum by the disease, and that anorectal manometric studies can be useful to detect such dysfunction in patients with SSc, even before clinical symptoms.",
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Kim, KC, Park, HJ, Lee, SK, Chung, JP, Lee, KS, Chon, CY & Park, IS 1996, 'Anorectal dysfunction in systemic sclerosis', Journal of Korean medical science, vol. 11, no. 3, pp. 244-249. https://doi.org/10.3346/jkms.1996.11.3.244

Anorectal dysfunction in systemic sclerosis. / Kim, Kyung Chul; Park, Hyo Jin; Lee, Soo Kon; Chung, Jun Pyo; Lee, Kwan Sik; Chon, Chae Yoon; Park, In Suh.

In: Journal of Korean medical science, Vol. 11, No. 3, 01.01.1996, p. 244-249.

Research output: Contribution to journalArticle

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