Anterior cingulotomy for refractory obsessive-compulsive disorder

C. H. Kim, JinWoo Chang, Min Seong Koo, J. W. Kim, H. S. Suh, I. H. Park, H. S. Lee

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

Objective: This study was designed to prospectively investigate the efficacy and cognitive adverse effects of stereotactic bilateral anterior cingulotomy as a treatment for refractory obsessive-compulsive (OCD) patients for 12 months. Method: Patients were eligible if they had severe OCD and rigorous treatments had been unsuccessful. Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Clinical Global Impression (CGI) and neuropsychological tests were used to assess the efficacy and cognitive changes of cingulotomy before and 12 months after operation. Results: The mean improvement rate of the Y-BOCS scores achieved from baseline was 36.0%. Out of 14 patients six met responder criteria; 35% or higher improvement rate on Y-BOCS and CGI improvement of very much or much better at 12-month follow-up. There was no significant cognitive dysfunction after cingulotomy. Conclusion: Anterior cingulotomy shows few cognitive adverse effects, with about half of the OCD patients demonstrating significant symptomatic improvement.

Original languageEnglish
Pages (from-to)283-290
Number of pages8
JournalActa Psychiatrica Scandinavica
Volume107
Issue number4
DOIs
Publication statusPublished - 2003 Apr 1

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Obsessive-Compulsive Disorder
Neuropsychological Tests
Therapeutics

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Cite this

Kim, C. H., Chang, J., Koo, M. S., Kim, J. W., Suh, H. S., Park, I. H., & Lee, H. S. (2003). Anterior cingulotomy for refractory obsessive-compulsive disorder. Acta Psychiatrica Scandinavica, 107(4), 283-290. https://doi.org/10.1034/j.1600-0447.2003.00087.x
Kim, C. H. ; Chang, JinWoo ; Koo, Min Seong ; Kim, J. W. ; Suh, H. S. ; Park, I. H. ; Lee, H. S. / Anterior cingulotomy for refractory obsessive-compulsive disorder. In: Acta Psychiatrica Scandinavica. 2003 ; Vol. 107, No. 4. pp. 283-290.
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Anterior cingulotomy for refractory obsessive-compulsive disorder. / Kim, C. H.; Chang, JinWoo; Koo, Min Seong; Kim, J. W.; Suh, H. S.; Park, I. H.; Lee, H. S.

In: Acta Psychiatrica Scandinavica, Vol. 107, No. 4, 01.04.2003, p. 283-290.

Research output: Contribution to journalArticle

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