Abstract
Non acetal-type derivatives at C-12 of artemisinin and their novel dimers including a fullerene conjugate were synthesized and some of them showed potent in vivo antiangiogenic activity on chorioallantoic membrane higher than or comparable to those of fumagillin and thalidomide.
Original language | English |
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Pages (from-to) | 1227-1230 |
Number of pages | 4 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 16 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2006 Mar 1 |
Bibliographical note
Funding Information:This work was supported by the Korea Research Foundation Grant (KRF-2003-015-C00380). We express our thanks to CKD Corp. for providing fumagillin.
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry