Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane

Mankil Jung; Jungae Tak; Won Yoon Chung; Kwang Kyun Park

doi:10.1016/j.bmcl.2005.11.074

Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane

Mankil Jung, Jungae Tak, Won Yoon Chung, Kwang Kyun Park

Department of Oral Biology

Research output: Contribution to journal › Article

34 Citations (Scopus)

Abstract

Non acetal-type derivatives at C-12 of artemisinin and their novel dimers including a fullerene conjugate were synthesized and some of them showed potent in vivo antiangiogenic activity on chorioallantoic membrane higher than or comparable to those of fumagillin and thalidomide.

Original language	English
Pages (from-to)	1227-1230
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	16
Issue number	5
DOIs	https://doi.org/10.1016/j.bmcl.2005.11.074
Publication status	Published - 2006 Mar 1

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All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Cite this

Jung, M., Tak, J., Chung, W. Y., & Park, K. K. (2006). Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane. Bioorganic and Medicinal Chemistry Letters, 16(5), 1227-1230. https://doi.org/10.1016/j.bmcl.2005.11.074

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Access to Document

10.1016/j.bmcl.2005.11.074