Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane

Mankil Jung, Jungae Tak, Won Yoon Chung, Kwang Kyun Park

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Non acetal-type derivatives at C-12 of artemisinin and their novel dimers including a fullerene conjugate were synthesized and some of them showed potent in vivo antiangiogenic activity on chorioallantoic membrane higher than or comparable to those of fumagillin and thalidomide.

Original languageEnglish
Pages (from-to)1227-1230
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume16
Issue number5
DOIs
Publication statusPublished - 2006 Mar 1

Bibliographical note

Funding Information:
This work was supported by the Korea Research Foundation Grant (KRF-2003-015-C00380). We express our thanks to CKD Corp. for providing fumagillin.

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Antiangiogenic activity of deoxoartemisinin derivatives on chorioallantoic membrane'. Together they form a unique fingerprint.

Cite this