Antibacterial activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb. against foodborne pathogens

Young Lee Lee, Jae Seok Shim, Yaya Rukayadi, Jae-Kwan Hwang

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Xanthorrhizol, isolated from the ethanol extract of Curcuma xanthorrhiza Roxb., is a sesquiterpene compound with a molecular weight of 218. The aim of this study was to investigate the antibacterial activity of xanthorrhizol against foodborne pathogens. The antibacterial activity of xanthorrhizol was measured in terms of the MIC and the MBC. MICs and MBCs of xanthorrhizol against Bacillus cereus, Clostridium perfringens, Listeria monocytogenes, Staphylococcus aureus, Salmonella Typhimurium, and Vibrio parahaemolyticus were 8, 16, 8, 8, 16, 8 μg/ml and 16, 32, 16, 16, 16, 16 μg/ml, respectively. The bactericidal study, as determined by the viable cell count method, revealed that xanthorrhizol treatment at 4 X MIC reduced viable cells by at least 6 to 8 log for all six foodborne pathogens in 4 h. Xanthorrhizol maintained its antibacterial activity after thermal treatments (121°C, 15 min) under various pH ranges (pH 3.0, 7.0, and 11.0). These results strongly suggest that xanthorrhizol, conferring strong antibacterial activity with thermal and pH stability, can be effectively used as a natural preservative to prevent the growth of foodborne pathogens.

Original languageEnglish
Pages (from-to)1926-1930
Number of pages5
JournalJournal of Food Protection
Volume71
Issue number9
DOIs
Publication statusPublished - 2008 Jan 1

Fingerprint

Curcuma zanthorrhiza
Curcuma
food pathogens
Vibrio parahaemolyticus
Clostridium perfringens
Bacillus cereus
preservatives
Salmonella Typhimurium
sesquiterpenoids
Listeria monocytogenes
Staphylococcus aureus
ethanol
heat treatment
cells
molecular weight
heat
Hot Temperature
extracts
Sesquiterpenes
Salmonella typhimurium

All Science Journal Classification (ASJC) codes

  • Food Science
  • Microbiology

Cite this

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title = "Antibacterial activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb. against foodborne pathogens",
abstract = "Xanthorrhizol, isolated from the ethanol extract of Curcuma xanthorrhiza Roxb., is a sesquiterpene compound with a molecular weight of 218. The aim of this study was to investigate the antibacterial activity of xanthorrhizol against foodborne pathogens. The antibacterial activity of xanthorrhizol was measured in terms of the MIC and the MBC. MICs and MBCs of xanthorrhizol against Bacillus cereus, Clostridium perfringens, Listeria monocytogenes, Staphylococcus aureus, Salmonella Typhimurium, and Vibrio parahaemolyticus were 8, 16, 8, 8, 16, 8 μg/ml and 16, 32, 16, 16, 16, 16 μg/ml, respectively. The bactericidal study, as determined by the viable cell count method, revealed that xanthorrhizol treatment at 4 X MIC reduced viable cells by at least 6 to 8 log for all six foodborne pathogens in 4 h. Xanthorrhizol maintained its antibacterial activity after thermal treatments (121°C, 15 min) under various pH ranges (pH 3.0, 7.0, and 11.0). These results strongly suggest that xanthorrhizol, conferring strong antibacterial activity with thermal and pH stability, can be effectively used as a natural preservative to prevent the growth of foodborne pathogens.",
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Antibacterial activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb. against foodborne pathogens. / Lee, Young Lee; Shim, Jae Seok; Rukayadi, Yaya; Hwang, Jae-Kwan.

In: Journal of Food Protection, Vol. 71, No. 9, 01.01.2008, p. 1926-1930.

Research output: Contribution to journalArticle

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