Antibacterial behaviour of quaternized poly(vinyl chloride)-g-poly(4-vinyl pyridine) graft copolymers

Madhumita Patel; Rajkumar Patel; Won Seok Chi; Jong Hak Kim; Jung Suk Sung

doi:10.1007/s10118-015-1577-3

Antibacterial behaviour of quaternized poly(vinyl chloride)-g-poly(4-vinyl pyridine) graft copolymers

Madhumita Patel, Rajkumar Patel, Won Seok Chi, Jong Hak Kim, Jung Suk Sung

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Amphiphilic graft copolymers consisting of poly(vinyl chloride) (PVC) main chains and poly(4-vinyl pyridine) (P4VP) side chains were synthesized via atom transfer radical polymerization (ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4VP graft copolymers was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (¹H-NMR). Transmission electron microscope (TEM) and small angle X-ray scattering (SAXS) analysis showed that PVC-g-P4VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-g-P4VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), and Pseudomonas aeruginosa (P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP (46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell.

Original language	English
Pages (from-to)	265-274
Number of pages	10
Journal	Chinese Journal of Polymer Science (English Edition)
Volume	33
Issue number	2
DOIs	https://doi.org/10.1007/s10118-015-1577-3
Publication status	Published - 2015 Feb

Bibliographical note

Publisher Copyright:
© 2015, Chinese Chemical Society, Institute of Chemistry, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg.

All Science Journal Classification (ASJC) codes

Chemical Engineering(all)
Organic Chemistry
Polymers and Plastics

Access to Document

10.1007/s10118-015-1577-3

Fingerprint Dive into the research topics of 'Antibacterial behaviour of quaternized poly(vinyl chloride)-g-poly(4-vinyl pyridine) graft copolymers'. Together they form a unique fingerprint.

Cite this

@article{025ebbd616a547089f2a79775ce49207,

title = "Antibacterial behaviour of quaternized poly(vinyl chloride)-g-poly(4-vinyl pyridine) graft copolymers",

abstract = "Amphiphilic graft copolymers consisting of poly(vinyl chloride) (PVC) main chains and poly(4-vinyl pyridine) (P4VP) side chains were synthesized via atom transfer radical polymerization (ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4VP graft copolymers was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). Transmission electron microscope (TEM) and small angle X-ray scattering (SAXS) analysis showed that PVC-g-P4VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-g-P4VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), and Pseudomonas aeruginosa (P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP (46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell.",

author = "Madhumita Patel and Rajkumar Patel and Chi, {Won Seok} and Kim, {Jong Hak} and Sung, {Jung Suk}",

note = "Publisher Copyright: {\textcopyright} 2015, Chinese Chemical Society, Institute of Chemistry, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg.",

year = "2015",

month = feb,

doi = "10.1007/s10118-015-1577-3",

language = "English",

volume = "33",

pages = "265--274",

journal = "Chinese Journal of Polymer Science (English Edition)",

issn = "0256-7679",

publisher = "Springer Verlag",

number = "2",

}

TY - JOUR

T1 - Antibacterial behaviour of quaternized poly(vinyl chloride)-g-poly(4-vinyl pyridine) graft copolymers

AU - Patel, Madhumita

AU - Patel, Rajkumar

AU - Chi, Won Seok

AU - Kim, Jong Hak

AU - Sung, Jung Suk

PY - 2015/2

Y1 - 2015/2

N2 - Amphiphilic graft copolymers consisting of poly(vinyl chloride) (PVC) main chains and poly(4-vinyl pyridine) (P4VP) side chains were synthesized via atom transfer radical polymerization (ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4VP graft copolymers was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). Transmission electron microscope (TEM) and small angle X-ray scattering (SAXS) analysis showed that PVC-g-P4VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-g-P4VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), and Pseudomonas aeruginosa (P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP (46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell.

AB - Amphiphilic graft copolymers consisting of poly(vinyl chloride) (PVC) main chains and poly(4-vinyl pyridine) (P4VP) side chains were synthesized via atom transfer radical polymerization (ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4VP graft copolymers was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). Transmission electron microscope (TEM) and small angle X-ray scattering (SAXS) analysis showed that PVC-g-P4VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-g-P4VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), and Pseudomonas aeruginosa (P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP (46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell.

UR - http://www.scopus.com/inward/record.url?scp=84919780392&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84919780392&partnerID=8YFLogxK

U2 - 10.1007/s10118-015-1577-3

DO - 10.1007/s10118-015-1577-3

M3 - Article

AN - SCOPUS:84919780392

VL - 33

SP - 265

EP - 274

JO - Chinese Journal of Polymer Science (English Edition)

JF - Chinese Journal of Polymer Science (English Edition)

SN - 0256-7679

IS - 2

ER -

Antibacterial behaviour of quaternized poly(vinyl chloride)-g-poly(4-vinyl pyridine) graft copolymers

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Cite this