Antibacterial poly (3,4-ethylenedioxythiophene):poly(styrene-sulfonate)/agarose nanocomposite hydrogels with thermo-processability and self-healing

Youngsang Ko, Jeonghun Kim, Ho Young Jeong, Goomin Kwon, Dabum Kim, Minhee Ku, Jaemoon Yang, Yusuke Yamauchi, Hae Yeong Kim, Chanhui Lee, Jungmok You

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Recently, Near-infrared (NIR)-induced photothermal killing of pathogenic bacteria has received considerable attention due to the increase in antibiotic resistant bacteria. In this paper, we report a simple aqueous solution-based strategy to construct an effective photothermal nanocomposite composed of poly(3,4-ethylenedioxythiophene):poly(styrene-sulfonate) (PEDOT:PSS) and agarose with thermo-processability, light triggered self-healing, and excellent antibacterial activity. Our experiments revealed that PEDOT:PSS/agarose was easily coated on both a 2D glass substrate and 3D cotton structure. Additionally, PEDOT:PSS/agarose can be designed into free-standing objects of diverse shape as well as restored through an NIR light-induced self-healing effect after damage. Taking advantage of strong NIR light absorption, PEDOT:PSS/agarose exhibited a sharp temperature increase of 24.5 °C during NIR exposure for 100 s. More importantly, we demonstrated that the temperature increase on PEDOT:PSS/agarose via photothermal conversion resulted in the rapid and effective killing of nearly 100% of the pathogenic bacteria within 2 min of NIR irradiation.

Original languageEnglish
Pages (from-to)26-34
Number of pages9
JournalCarbohydrate Polymers
Volume203
DOIs
Publication statusPublished - 2019 Jan 1

Bibliographical note

Funding Information:
This study was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIP) (No. 2017R1C1B2010867, 2018R1D1A1B07047874), a grant from Kyung Hee University in 2015 (KHU- 20152129), and a Cooperative Research Program for Agriculture Science and Technology Development (Project No. PJ01279701) Rural Development Administration, Republic of Korea.

Publisher Copyright:
© 2018 Elsevier Ltd

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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