Antibiotic use in patients with abdominal injuries

Guideline by the Korean Society of Acute Care Surgery

Korean Society of Acute Care Surgery (KSACS) Clinical Research Group

Research output: Contribution to journalArticle

Abstract

Purpose: A task force appointed by the Korean Society of Acute Care Surgery reviewed previously published guidelines on antibiotic use in patients with abdominal injuries and adapted guidelines for Korea. Methods: Four guidelines were assessed using the Appraisal of Guidelines for Research and Evaluation II instrument. Five topics were considered: indication for antibiotics, time until first antibiotic use, antibiotic therapy duration, appropriate antibiotics, and antibiotic use in abdominal trauma patients with hemorrhagic shock. Results: Patients requiring surgery need preoperative prophylactic antibiotics. Patients who do not require surgery do not need antibiotics. Antibiotics should be administered as soon as possible after injury. In the absence of hollow viscus injury, no additional antibiotic doses are needed. If hollow viscus injury is repaired within 12 hours, antibiotics should be continued for ≤ 24 hours. If hollow viscus injury is repaired after 12 hours, antibiotics should be limited to 7 days. Antibiotics can be administered for ≥7 days if hollow viscus injury is incompletely repaired or clinical signs persist. Broad-spectrum aerobic and anaerobic coverage antibiotics are preferred as the initial antibiotics. Second-generation cephalosporins are the recommended initial antibiotics. Third-generation cephalosporins are alternative choices. For hemorrhagic shock, the antibiotic dose may be increased twofold or threefold and repeated after transfusion of every 10 units of blood until there is no further blood loss. Conclusion: Although this guideline was drafted through adaptation of other guidelines, it may be meaningful in that it provides a consensus on the use of antibiotics in abdominal trauma patients in Korea.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalAnnals of Surgical Treatment and Research
Volume96
Issue number1
DOIs
Publication statusPublished - 2019 Jan 1

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Abdominal Injuries
Guidelines
Anti-Bacterial Agents
Viscera
Wounds and Injuries
Hemorrhagic Shock
Cephalosporins
Korea

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Korean Society of Acute Care Surgery (KSACS) Clinical Research Group. / Antibiotic use in patients with abdominal injuries : Guideline by the Korean Society of Acute Care Surgery. In: Annals of Surgical Treatment and Research. 2019 ; Vol. 96, No. 1. pp. 1-7.
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abstract = "Purpose: A task force appointed by the Korean Society of Acute Care Surgery reviewed previously published guidelines on antibiotic use in patients with abdominal injuries and adapted guidelines for Korea. Methods: Four guidelines were assessed using the Appraisal of Guidelines for Research and Evaluation II instrument. Five topics were considered: indication for antibiotics, time until first antibiotic use, antibiotic therapy duration, appropriate antibiotics, and antibiotic use in abdominal trauma patients with hemorrhagic shock. Results: Patients requiring surgery need preoperative prophylactic antibiotics. Patients who do not require surgery do not need antibiotics. Antibiotics should be administered as soon as possible after injury. In the absence of hollow viscus injury, no additional antibiotic doses are needed. If hollow viscus injury is repaired within 12 hours, antibiotics should be continued for ≤ 24 hours. If hollow viscus injury is repaired after 12 hours, antibiotics should be limited to 7 days. Antibiotics can be administered for ≥7 days if hollow viscus injury is incompletely repaired or clinical signs persist. Broad-spectrum aerobic and anaerobic coverage antibiotics are preferred as the initial antibiotics. Second-generation cephalosporins are the recommended initial antibiotics. Third-generation cephalosporins are alternative choices. For hemorrhagic shock, the antibiotic dose may be increased twofold or threefold and repeated after transfusion of every 10 units of blood until there is no further blood loss. Conclusion: Although this guideline was drafted through adaptation of other guidelines, it may be meaningful in that it provides a consensus on the use of antibiotics in abdominal trauma patients in Korea.",
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Antibiotic use in patients with abdominal injuries : Guideline by the Korean Society of Acute Care Surgery. / Korean Society of Acute Care Surgery (KSACS) Clinical Research Group.

In: Annals of Surgical Treatment and Research, Vol. 96, No. 1, 01.01.2019, p. 1-7.

Research output: Contribution to journalArticle

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AU - Kang, Wu Seong

AU - Keum, Min Ae

AU - Sul, Young Hoon

AU - Lee, Dae Sang

AU - Cho, Hangjoo

AU - Lee, Gil Jae

AU - Lee, JaeGil

AU - Hong, Suk Kyung

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